Results 81 to 90 of about 9,523,481 (306)

Preparation of intact bovine tail intervertebral discs for organ culture

open access: yes, 2012
The intervertebral disc (IVD) is the joint of the spine connecting vertebra to vertebra. It functions to transmit loading of the spine and give flexibility to the spine.
Chan, Chun Wai   +1 more
core   +1 more source

Plant Secondary metabolites production by in vitro culture

open access: yesBiotecnología Vegetal, 2011
Plant cell and tissue cultures are considered as an alternative source to the whole plant for the production of valuable compounds. Undifferentiated cell cultures have been extensively studied, but a large interest has also been shown in hairy roots and ...
Naivy Pérez-Alonso, Elio Jiménez
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The nerve center of organ engineering

open access: yesNature Communications
Engineering replacement organs is the next frontier in therapeutic technologies. Yet, the integration of innervation—critical for organ development, function, and homeostasis—remains underexplored.
Suradip Das   +5 more
doaj   +1 more source

Polymerase Chain Reaction and blood culture for diagnosis of canine sepsis

open access: yesCiência Rural, 2018
: Sepsis is characterized by the presence of organ dysfunction secondary to the dysregulated systemic inflammatory response associated with an infection, and has high mortality rates.
Marcelo Marques da Silveira   +8 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip

open access: yesCells
This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux’s seminal experiments in the 1880s, followed by the pioneering efforts of Ross ...
Lincoln Gozzi Moro   +8 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Piano and organ workers' official journal.

open access: yes, 1905
"Issued by Piano and Organ Workers International Union of America."Description based on: Vol. 3, no. 1 (Jan.
Piano and Organ Workers' International Union of America.
core  

Real-Time Label-Free Biosensing with Gold Nanoprisms: Towards Advanced Cell Monitoring in Microfluidic Platforms [PDF]

open access: yesEPJ Web of Conferences
We present a nanoplasmonic biosensor based on periodic arrays of gold nanoprisms, engineered for high-sensitivity and label-free detection of biomolecular interactions. Integrated within a microfluidic platform, the biosensor is designed to operate under
Colombelli Adriano   +5 more
doaj   +1 more source

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