Results 11 to 20 of about 790,004 (346)

Latest culture techniques: cracking the secrets of bone marrow to mass-produce erythrocytes and platelets ex vivo

open access: yesHaematologica, 2021
Since the dawn of medicine, scientists have carefully observed, modeled and interpreted the human body to improve healthcare. At the beginning there were drawings and paintings, now there is three-dimensional modeling.
C. D. Di Buduo   +6 more
semanticscholar   +1 more source

An improved organ explant culture method reveals stem cell lineage dynamics in the adult Drosophila intestine

open access: yeseLife, 2022
In recent years, live-imaging techniques have been developed for the adult midgut of Drosophila melanogaster that allow temporal characterization of key processes involved in stem cell and tissue homeostasis.
Marco Marchetti   +2 more
doaj   +1 more source

Digital Twins for Tissue Culture Techniques—Concepts, Expectations, and State of the Art

open access: yes, 2021
Techniques to provide in vitro tissue culture have undergone significant changes during the last decades, and current applications involve interactions of cells and organoids, three-dimensional cell co-cultures, and organ/body-on-chip tools.
J. Möller, R. Pörtner
semanticscholar   +1 more source

Tumor organoids: synergistic applications, current challenges, and future prospects in cancer therapy

open access: yesCancer Communications, 2021
Patient‐derived cancer cells (PDCs) and patient‐derived xenografts (PDXs) are often used as tumor models, but have many shortcomings. PDCs not only lack diversity in terms of cell type, spatial organization, and microenvironment but also have adverse ...
Jingjing Qu   +4 more
doaj   +1 more source

Editorial for the Special Issue on Organs-on-Chips

open access: yesMicromachines, 2020
Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices to model functional units of organs [...]
Yu-suke Torisawa, Yi-Chung Tung
doaj   +1 more source

Breaking the Third Wall: Implementing 3D-Printing Techniques to Expand the Complexity and Abilities of Multi-Organ-on-a-Chip Devices

open access: yesMicromachines, 2021
The understanding that systemic context and tissue crosstalk are essential keys for bridging the gap between in vitro models and in vivo conditions led to a growing effort in the last decade to develop advanced multi-organ-on-a-chip devices.
Yoel Goldstein   +7 more
semanticscholar   +1 more source

Organs-on-Chips Platforms Are Everywhere: A Zoom on Biomedical Investigation

open access: yesBioengineering, 2022
Over the decades, conventional in vitro culture systems and animal models have been used to study physiology, nutrient or drug metabolisms including mechanical and physiopathological aspects.
Mohamed Zommiti   +8 more
doaj   +1 more source

A review on the evolution of methods for intestinal in vitro organ culture and its application in veterinary science [PDF]

open access: yesVeterinary World, 2023
Different techniques have been reported in studies of intestinal in vitro organ culture (IVOC). A robust compilation of all available methods is lacking in the literature, making it difficult to choose a method that corresponds to the study's demands. In
Barbara Ribeiro de Souza Cortez   +1 more
doaj   +1 more source

Is It Time to Start Transitioning From 2D to 3D Cell Culture?

open access: yesFrontiers in Molecular Biosciences, 2020
Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen   +5 more
doaj   +1 more source

Next Generation Sequencing for Diagnosis of Leptospirosis Combined With Multiple Organ Failure: A Case Report and Literature Review

open access: yesFrontiers in Medicine, 2022
IntroductionLeptospirosis poses a major threat to human life. The disease spectrum ranges from a nearly undetectable presentation to severe multi-organ dysfunction and death.
Juan Lu   +3 more
doaj   +1 more source

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