Results 211 to 220 of about 464,944 (323)

Applications in osteochondral organoids for osteoarthritis research: from pathomimetic modeling to tissue engineering repair. [PDF]

Front Bioeng Biotechnol
Jiao Y, Lu S, Zhang J, Zhen J.
europepmc   +1 more source

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Early-Onset Candidemia in Adult Intensive Care Units. [PDF]

Diagnostics (Basel)
Mouratidou C, Tsakiri K, Dourliou V, Marneri A, Stougianni M, Pavlidis E.   +5 more
europepmc   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Revolutionizing Biomedical Research: Unveiling the Power of Microphysiological Systems with Advanced Assays, Integrated Sensor Technologies, and Real-Time Monitoring. [PDF]

ACS Omega
Samantasinghar A, Sunildutt N, Ahmed F, Memon FH, Kang C, Choi KH.   +5 more
europepmc   +1 more source

Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring

Advanced Healthcare Materials, EarlyView.
This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang, Yujin Ahn, Semin Kwon, Tianhao Yu, Yumin Dai, Julia Walsh, Joo Hun Lee, Sang Mok Park, Seul Ah Lee, Murtuza Peerbhai, Chandan K. Sen, Hyowon Lee, Young L. Kim, Hyunjoon Kong, Chi Hwan Lee   +14 more
wiley   +1 more source

Current Techniques of Gene Editing in Pigs for Xenotransplantation. [PDF]

Transpl Int
Galli C.
europepmc   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Microfluidic Systems to Mimic the Blood-Brain Barrier: from Market to Engineering Challenges and Perspectives. [PDF]

ACS Biomater Sci Eng
da Silva GG, Sacomani DP, de Carvalho BG, Porcionatto MA, Gobbi A, Lima RS, de la Torre LG.   +6 more
europepmc   +1 more source

Robust pH Sensing Using a Graphene Oxide and Covalent Organic Frameworks Composite for Gastro‐esophageal Reflux Disease Diagnosis

Advanced Healthcare Materials, EarlyView.
A stable composite pH sensor is developed by coating graphene oxide (GO) nanosheets with covalent organic frameworks (COFs) to improve stability and sensitivity in acidic environments. The GO/COFs sensor demonstrates high selectivity, linearity, and biocompatibility, offering a promising strategy for continuous pH monitoring in gastro‐esophageal reflux
Ahmed H. M. Salem, Jianhui Zhang, Ashley Lam, Haowei Wang, Umber Cheema, Laurence B. Lovat, Manish K. Tiwari   +6 more
wiley   +1 more source