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The understanding that systemic context and tissue crosstalk are essential keys for bridging the gap between in vitro models and in vivo conditions led to a growing effort in the last decade to develop advanced multi-organ-on-a-chip devices.
Yoel Goldstein +7 more
semanticscholar +1 more source
Organs-on-Chips Platforms Are Everywhere: A Zoom on Biomedical Investigation
Over the decades, conventional in vitro culture systems and animal models have been used to study physiology, nutrient or drug metabolisms including mechanical and physiopathological aspects.
Mohamed Zommiti +8 more
doaj +1 more source
A review on the evolution of methods for intestinal in vitro organ culture and its application in veterinary science [PDF]
Different techniques have been reported in studies of intestinal in vitro organ culture (IVOC). A robust compilation of all available methods is lacking in the literature, making it difficult to choose a method that corresponds to the study's demands. In
Barbara Ribeiro de Souza Cortez +1 more
doaj +1 more source
Is It Time to Start Transitioning From 2D to 3D Cell Culture?
Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen +5 more
doaj +1 more source
Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology and physiology of their in vivo counterparts. Here, we have developed a multiplex platform that
Spencer T. Seiler +14 more
doaj +1 more source
IntroductionLeptospirosis poses a major threat to human life. The disease spectrum ranges from a nearly undetectable presentation to severe multi-organ dysfunction and death.
Juan Lu +3 more
doaj +1 more source
Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
core +2 more sources
The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C +15 more
core +2 more sources
Intestine Explants in Organ Culture: A Tool to Broaden the Regenerative Studies in Echinoderms
The cellular events underlying intestine regrowth in the sea cucumber Holothuria glaberrima have been described by our group. Currently, the molecular and signaling mechanisms involved in this process are being explored.
Samir A. Bello +1 more
doaj +1 more source
Growth of donor-derived dendritic cells from the bone marrow of murine liver auograft recipients in response to granulocyte/macrophage colony-stimulating factor [PDF]
Allografts of the liver, which has a comparatively heavy leukocyte content compared with other vascularized organs, are accepted permanently across major histocompatibility complex barriers in many murine strain combinations without immunosuppressive ...
Fu, F +9 more
core +1 more source

