Results 21 to 30 of about 680,344 (360)

Next Generation Sequencing for Diagnosis of Leptospirosis Combined With Multiple Organ Failure: A Case Report and Literature Review

Frontiers in Medicine, 2022
IntroductionLeptospirosis poses a major threat to human life. The disease spectrum ranges from a nearly undetectable presentation to severe multi-organ dysfunction and death.
Juan Lu, Juan Hu, Shanshan Yu, Lanjuan Li   +3 more
doaj   +1 more source

Modular automated microfluidic cell culture platform reduces glycolytic stress in cerebral cortex organoids

Scientific Reports, 2022
Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology and physiology of their in vivo counterparts. Here, we have developed a multiplex platform that
Spencer T. Seiler, Gary L. Mantalas, John Selberg, Sergio Cordero, Sebastian Torres-Montoya, Pierre V. Baudin, Victoria T. Ly, Finn Amend, Liam Tran, Ryan N. Hoffman, Marco Rolandi, Richard E. Green, David Haussler, Sofie R. Salama, Mircea Teodorescu   +14 more
doaj   +1 more source

Intestine Explants in Organ Culture: A Tool to Broaden the Regenerative Studies in Echinoderms

Journal of Marine Science and Engineering, 2022
The cellular events underlying intestine regrowth in the sea cucumber Holothuria glaberrima have been described by our group. Currently, the molecular and signaling mechanisms involved in this process are being explored.
Samir A. Bello, José E. García-Arrarás   +1 more
doaj   +1 more source

Frontiers in medicine : Looking beyond organ transplant

Journal of Marine Medical Society, 2015
The introduction of organ transplantation has revolutionized outcomes in end stage organ failure. Concepts of Brain death & beating heart donors make organs more available. Yet wait lists for organs are long and the techniques of immuno suppression still
Tapan Sinha
doaj   +1 more source

Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]

, 2002
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Al-Batran, Salah, Baumgartner, Reinhold, Bergner, Albrecht, Castro, Mirna, Gamarra, Fernando, Hautmann, Hubert, Huber, Rudolf M., Maier, Irmgard, Wagner, Simon   +8 more
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The changing immunology of organ transplantation [PDF]

, 1995
The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft.
Demetris AJ, Lu L, Lu L, Murase N, Starzl TE, Starzl TE, Starzl TE, Starzl TE, Steinman RM, Streilein JW, Thomas JM   +10 more
core   +1 more source

A High-Throughput and Uniform Amplification Method for Cell Spheroids

Micromachines, 2022
Cell culture is an important life science technology. Compared with the traditional two-dimensional cell culture, three-dimensional cell culture can simulate the natural environment and structure specificity of cell growth in vivo. As such, it has become
Liyuan Liu, Haixia Liu, Xiaowen Huang, Xiaoli Liu, Chengyun Zheng   +4 more
doaj   +1 more source

Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]

, 2001
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht, Gamarra, Fernando, Harréus, Ulrich A., Huber, Rudolf M., Juchhoff, Jutta, Kastenbauer, Ernst R., Kleinsasser, Norbert H., Wallner, Barbara C.   +7 more
core   +1 more source

Differentiation of Mesenchymal Stem Cells Into Cardiac-like Cells by Co-induction of Lentiviruses Containing Mir-1 and Myocd in Chitosan Collagen Hydrogel Scaffold

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: Cardiovascular disease is one of the leading causes of death worldwide. Mesenchymal stem cells (MSCs) are one of the most common sources of cell-based therapies in heart regeneration.
Samaneh Khazaei, Masoud Soleimani, Zohreh Hojati, Seyyed hossein Ahmaditafti   +3 more
doaj  

Opportunities for organoids as new models of aging. [PDF]

, 2018
The biology of aging is challenging to study, particularly in humans. As a result, model organisms are used to approximate the physiological context of aging in humans. However, the best model organisms remain expensive and time-consuming to use.
Antonica, Arora, Astashkina, Auger, Aw, Azpurua, Barbero, Barkauskas, Barkauskas, Barker, Bartfeld, Behjati, Belmin, Ben-Ze’ev, Bhumiratana, Blau, Blokzijl, Brack, Broutier, Busuttil, Caron, Caughey, Cerchiari, Chambers, Chang, Chaudhuri, Choi, Cornacchia, Crabb, Danahay, Dekkers, Dos Santos, Dye, Eiraku, Elahy, Engevik, Freedman, Gao, Garbe, Gjorevski, Greider, Gullapalli, Hannum, Hansen, Hegab, Heintz, Hibiya, Hohwieler, Horvath, Htwe, Huch, Huch, Jennifer L. Hu, Jones, Jung, Karthaus, Kolesky, Koo, Kwong, Lang, Lee, Lee, Levental, Li, Li, Lindahl, Linnemann, Liu, Lozito, Lyons, López-Otín, L’Heureux, Madden, Marciniak, Mark A. LaBarge, Matsui, Mattison, McElwee, Meerwaldt, Mertens, Messner, Michael E. Todhunter, Miller, Moore, Moore, Morizane, Murrow, Myers, Nalapareddy, Nasto, Nelson, Nevalainen, Nguyen-Ngoc, Nicholas, Noguchi, Ootani, O’Brien, Pageon, Pang, Parrinello, Pauli, Phillip, Plaks, Pribluda, Qian, Raja, Rangarajan, Rodriguez-Teja, Ruan, Sancar, Sato, Schütte, Seok, Simian, Singh, Squires, Stampfer, Stearns-Reider, Stojadinovic, Sun, Takasato, Takebe, Tan, Tanos, Toda, Todhunter, Turco, Tzatzalos, van Vliet, Vanhooren, Vernetti, Verzijl, Villadsen, Villeda, Voytik-Harbin, Watson, Williams, Wilson, Workman, Wu, Wylie, Xiang, Yilmaz, Zev J. Gartner, Zhang, Zhang   +145 more
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