Results 51 to 60 of about 790,004 (346)

The effect of creatine on the ex vivo contractility of myometrial tissue derived from term pregnant mice and women

Journal of the International Society of Sports Nutrition
Background There is evidence that the smooth muscle layer of the uterus, the myometrium, uses creatine to support energy turnover in pregnancy and labour.
Alexus J. Brown, Jeff Reese, Jennifer L. Herington, Stacey J. Ellery   +3 more
doaj   +1 more source

Generation and evaluation of input values for computational analysis of transport processes within tissue cultures

Engineering in Life Sciences, 2022
Techniques for tissue culture have seen significant advances during the last decades and novel 3D cell culture systems have become available. To control their high complexity, experimental techniques and their Digital Twins (modelling and computational ...
Ehsan Fattahi, Shahed Taheri, Arndt F. Schilling, Thomas Becker, Ralf Pörtner   +4 more
doaj   +1 more source

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C, Chapman, Hal A, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Katzen, Jeremy, Kotton, Darrell N, Morrisey, Edward E, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J   +15 more
core   +1 more source

3D cell culture models and organ‐on‐a‐chip: Meet separation science and mass spectrometry

Electrophoresis, 2019
In vitro derived simplified 3D representations of human organs or organ functionalities are predicted to play a major role in disease modeling, drug development, and personalized medicine, as they complement traditional cell line approaches and animal ...
A-jay Lin, F. S. Skottvoll, Simon Rayner, S. Pedersen‐Bjergaard, G. Sullivan, S. Krauss, S. Wilson, S. Harrison   +7 more
semanticscholar   +1 more source

In vitro spermatogenesis: A century‐long research journey, still half way around

Reproductive Medicine and Biology, 2018
Background Spermatogenesis is one of the most complicated cellular differentiation processes in a body. Researchers struggled to find and develop a micro‐environmental condition that can support the process in vitro.
Mitsuru Komeya, Takuya Sato, Takehiko Ogawa   +2 more
doaj   +1 more source

3D Cell Cultures: Evolution of an Ancient Tool for New Applications

Frontiers in Physiology, 2022
Recently, research is undergoing a drastic change in the application of the animal model as a unique investigation strategy, considering an alternative approach for the development of science for the future.
Andrea Cacciamali, Riccardo Villa, Silvia Dotti   +2 more
doaj   +1 more source

Evaluation of Somatic Embryogenesis Ability in Robusta Coffee (Coffea Canephora Pierre) [PDF]

, 2010
Embriogenesis somatik diharapkan sebagai metode perbanyakan tanaman yang sangat efektif pada kopi. Evaluasi dua jenis proses embriogenesis somatik, yaitu proses langsung dan tidak langsung akan bermanfaat untuk menggambarkan kemampuan proliferasi sel ...
Priyono, P. (Priyono)
core   +3 more sources

In vitro strategies for the enhancement of secondary metabolite production in plants: a review

Bulletin of the National Research Centre, 2022
Background Plants are the prime source of vital secondary metabolites (SMs) which are medicinally important for drug development, and these secondary metabolites are often used by plants in the various important tasks like defense against herbivory ...
Mohammad Afaan Fazili, Irfan Bashir, Mudasar Ahmad, Ubaid Yaqoob, Syed Naseem Geelani   +4 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source