Results 81 to 90 of about 680,344 (360)

Novel applications of plant tissue culture and conventional breeding techniques to space biology research [PDF]

, 2001
In the minds of many, plant cell and tissue culture may now be viewed as a well-developed technology. It has been all but reduced to a tool to solve practical problems and contribute to plant improvement.
Krikorian, Abraham D.
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

A Technique to Establish a Bacterial Infection Model in an Ex Vivo Organ Culture [PDF]

, 2023

openalex   +2 more sources

Online oxygen monitoring using integrated inkjet-printed sensors in a liver-on-a-chip system [PDF]

, 2018
The demand for real-time monitoring of cell functions and cell conditions has dramatically increased with the emergence of organ-on-a-chip (OOC) systems.
Gabriel Buguña, Gemma, Gracia Sancho, Jordi, Guimerà Villalba, Xavier, Illa, Xavi, Moya Lara, Ana, Ortega Ribera, Martí, Ramon, Eloi, Sowade, Enrico, Villa, Rosa, Zea, Miguel   +9 more
core   +2 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

The Physics of Living Neural Networks [PDF]

Physics Reports Volume 449, Issues 1-3, September 2007, Pages 54-76, 2010
Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture. Organization and connectivity are being measured quantitatively along with other physical quantities such as information, and are being related to function.
arxiv   +1 more source

Microphysiological systems in absorption, distribution, metabolism, and elimination sciences

Clinical and Translational Science, 2022
The use of microphysiological systems (MPS) to support absorption, distribution, metabolism, and elimination (ADME) sciences has grown substantially in the last decade, in part driven by regulatory demands to move away from traditional animal‐based ...
Kirk P. Van Ness, Francine Cesar, Catherine K. Yeung, Jonathan Himmelfarb, Edward J. Kelly   +4 more
doaj   +1 more source

Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. [PDF]

, 2017
Background:Recent studies have demonstrated the vital influence of commensal microbial communities on human health. The central role of the gut in the response to injury is well described; however, no prior studies have used culture-independent profiling
Calfee, Carolyn S, Callcut, Rachael A, Campion, Eric M, Christie, Sabrinah A, Cohen, Mitchell Jay, Conroy, Amanda S, Fadrosh, Douglas W, Howard, Benjamin M, Kornblith, Lucy Z, Lamere, Brandon J, Lynch, Susan, Nelson, Mary F   +11 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A Non-Phylogenetic Conceptual Network Architecture for Organizing Classes of Material Artifacts into Cultural Lineages [PDF]

In L. Carlson, C. Hoelscher, & T. Shipley (Eds.), Proceedings of the Annual Meeting of the Cognitive Science Society (pp. 2923-2928). Austin, TX: Cognitive Science Society. (2011), 2013
The application of phylogenetic techniques to the documentation of cultural history can present a distorted picture due to horizontal transmission and blending. Moreover, the units of cultural transmission must be communicable concepts, rather than conveniently measurable attributes, and relatedness between elements of culture often resides at the ...
arxiv