Results 101 to 110 of about 1,391,587 (398)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Deceased Organ Donation [PDF]

open access: yesAmerican Journal of Transplantation, 2016
SRTR uses data collected by OPTN to calculate metrics such as donation/conversion rate, organ yield, and rate of organs recovered for transplant but not transplanted. In 2014, 9252 eligible deaths were reported by organ procurement organizations, a slight increase from 8944 in 2012, and the donation/conversation rate was 73.4 eligible donors per 100 ...
Bert L Kasiske   +5 more
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

INFECTIONS IN THE POOL OF POTENTIAL ORGAN DONORS: IS IT ALWAYS CONTRAINDICATION TO DONATION?

open access: yesВестник трансплантологии и искусственных органов, 2011
The presence of certain infection in potential organ donors is significant problem for Russian Transplantology. The increase in detection of donor’s infections could be due to increase in general donor’s pool and also to utili- zation of modern ...
M. G. Minina
doaj   +1 more source

Peculiarities of the morphology of liver biopsy samples of donors above 60 years of age

open access: yesВестник трансплантологии и искусственных органов, 2020
Objective: to study the differences in the frequency of pathological processes in liver biopsy samples of donors older than 60 years (group 1) and donors currently recognized as “standard” by age – 60 years and younger (group 2). Material and methods. Of
I. M. Iljinsky   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Network meta-analysis of pharmacological treatment for antibody-mediated rejection after organ transplantation

open access: yesFrontiers in Immunology
ObjectiveThis study aims to assess the efficacy of pharmacological interventions in mitigating graft injury in transplant patients with antibody-mediated rejection (AMR) through a network meta-analysis (NMA).MethodsA search was conducted on databases ...
Junjie Sun   +8 more
doaj   +1 more source

Level of knowledge and attitude regarding organ donation: a community-based study from Karachi, Pakistan

open access: yesBMC Research Notes, 2019
The aim of our study was to assess the knowledge and attitude and to find out the statistics regarding public awareness of organ donation in Karachi.
F. Khalid   +5 more
semanticscholar   +1 more source

Does the Presence of a Measurable Blood Alcohol Level in a Potential Organ Donor Affect the Outcome of Liver Transplantation? [PDF]

open access: yes, 1991
The widespread application of hepatic transplantation has created a tremendous demand for donor organs. An assessment of donor parameters is thought to be important in selecting good donors; however, the criteria utilized have not been standardized. This
Ascher NL   +9 more
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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