Results 81 to 90 of about 49,997 (313)

TO SOME ORGANIZATIONAL ASPECTS OF ORGAN DONATION

Вестник трансплантологии и искусственных органов, 2010
Organization of organ donation for transplantation is one of the most actual problems of Russian Transplantolo- gy. Organ shortage for transplantation is perceiving in Russia through the improvement of organizational system of organ donation. An analysis
M. Minina
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mandated Choice for Organ Donation: Time to Give It a Try

, 1996
A severe shortage of organs greatly limits the ability to deliver the miracle of transplantation to people suffering from end-stage organ disease. Contributing to this shortage is a high rate of refusal among families who are asked for permission to ...
Spital, Aaron
core   +1 more source

Organ Donation for Social Change: A Systematic Review

, 2020
This chapter presents a critical review of the existing organ donation literature. The objective of this chapter is to identify the main gaps in the current body of literature on the organ donation context and the marketing discipline.
Weaven, S, Amani Alsalem, Thaichon, P, Park Thaichon, Alsalem, A, Scott Weaven   +5 more
core   +1 more source

The knowledges and opinions of ICU professionals about brain death and organ donation [PDF]

, 2017
[Abstract Not Available]International Society for Organ Donation and Procurement ...
Deniz Birtan, Aysegül Aksu, Esin Gulkaya Anik, Gülkaya Anık, Esin, Fadik Durmaz, Yavuz, Hanife, Kasim Okan Anik, Ahmet Cakiroglu, Aksu, Ayşegül, Anık, Kasım Okan, Birtan, Deniz, Çakıroğlu, Ahmet, Hanife Yavuz, Durmaz, Fadik   +13 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Network meta-analysis of pharmacological treatment for antibody-mediated rejection after organ transplantation

Frontiers in Immunology
ObjectiveThis study aims to assess the efficacy of pharmacological interventions in mitigating graft injury in transplant patients with antibody-mediated rejection (AMR) through a network meta-analysis (NMA).MethodsA search was conducted on databases ...
Junjie Sun, Yanqing Yu, Fu Huang, Fu Huang, Qiuwen Zhang, Lirong Zhu, Guining He, Haibin Li, Xuyong Sun   +8 more
doaj   +1 more source

INFECTIONS IN THE POOL OF POTENTIAL ORGAN DONORS: IS IT ALWAYS CONTRAINDICATION TO DONATION?

Вестник трансплантологии и искусственных органов, 2011
The presence of certain infection in potential organ donors is significant problem for Russian Transplantology. The increase in detection of donor’s infections could be due to increase in general donor’s pool and also to utili- zation of modern ...
M. G. Minina
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A socio-legal study on organ shortage in Malaysia

, 2012
Human organs are the most valuable gifts of life. Until today, through organ transplantation, thousands of lives have been saved and many more blessed with hope and happiness through a better quality of living.
Salwani, Farah
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