Results 91 to 100 of about 687,760 (261)

Optimizing Organ Donation After Euthanasia: A Critical Appraisal

This Critical Appraisal aims to explore the pharmacokinetics and pharmacodynamics of medications used in organ donors after euthanasia (ODE) and their impact on abdominal organ quality.
H. D. Lam, A. E. Braat, E. A. J. Alkemade, B. J. C. Hendriks, M. J. Coenraad, A. G. Baranski, I. P. J. Alwayn   +6 more
core   +1 more source

Organ donation awareness and attitude among Riyadh City Residents, Saudi Arabia

Journal of Nature and Science of Medicine, 2018
Introduction: Organ donation is widely contentious among the Saudi population though remains largely understudied. In the aim to understand the public perception of organ donation, willingness to donate, and the reasons for donation refusal, we carried ...
Aws Almufleh, Rasha Althebaity, Ali S Alamri, Nada A Al-Rashed, Eman H Alshehri, Lina Albalawi, Reem Alameer, Eman Hajr, Ismail A Raslan, Faisal A Alsaif   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Organ Donation and Transplant Ireland annual report 2015

, 2016
This report outlines the activities of Organ Donation and Transplant Ireland in 2015, including the rates of organ donation and transplantation in Ireland in ...

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Mandated Choice for Organ Donation: Time to Give It a Try

, 1996
A severe shortage of organs greatly limits the ability to deliver the miracle of transplantation to people suffering from end-stage organ disease. Contributing to this shortage is a high rate of refusal among families who are asked for permission to ...
Spital, Aaron
core   +1 more source

Organ Donation for Social Change: A Systematic Review

, 2020
This chapter presents a critical review of the existing organ donation literature. The objective of this chapter is to identify the main gaps in the current body of literature on the organ donation context and the marketing discipline.
Weaven, S, Amani Alsalem, Thaichon, P, Park Thaichon, Alsalem, A, Scott Weaven   +5 more
core   +1 more source

Integrated transcriptomic profiling of programmed cell death patterns unveils macrophage-hepatocyte crosstalk via THBS1-CD47 axis in hepatic ischemia-reperfusion injury

Frontiers in Immunology
BackgroundHepatic ischemia-reperfusion injury (HIRI) is clinically linked to post-transplant complications, yet the pathogenic role of programmed cell death (PCD) patterns in this process remains poorly delineated.
Manling Xie, Manling Xie, Manling Xie, Manling Xie, Changquan Zhang, Changquan Zhang, Changquan Zhang, Changquan Zhang, Lirong Zhu, Lirong Zhu, Lirong Zhu, Yongfeng Pei, Yongfeng Pei, Yongfeng Pei, Chunyan Liang, Chunyan Liang, Chunyan Liang, Lixin Fu, Lixin Fu, Lixin Fu, Haibin Li, Haibin Li, Haibin Li, Liugen Lan, Liugen Lan, Liugen Lan, Ning Wen, Ning Wen, Ning Wen, Jihua Wu, Jihua Wu, Jihua Wu, Xuyong Sun, Xuyong Sun, Xuyong Sun   +34 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Understanding decisions to communicate organ donation wishes: a narrative review

, 2013
Prior communication of organ donation wishes to family increases the likelihood of family consent for donation. However, many people have not shared their wishes.
Hyde, Melissa
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