Results 111 to 120 of about 2,193,065 (253)

NCIRF: an organ dose calculator for patients undergoing radiography and fluoroscopy. [PDF]

open access: yesBiomed Phys Eng Express, 2023
Lee C   +5 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Internal organ dose rate conversion coefficients of Japanese macaques to 134Cs,137Cs and 131I†. [PDF]

open access: yesJ Radiat Res, 2023
Takamura Y   +9 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Windlines. Volume 1, number 3 (March 2008)

open access: yes, 2008
Third issue of the American Organ Institute newsletter, contains pictures from the removal of the G. H.Hille Memorial Wurlitzer and the Moller Op. 5819, events at AOI during Spring 2008, "Technician's Corner" update about an average day at the organ shop,
American Organ Institute
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Windlines. Volume 5, number 2 (January 2012)

open access: yes, 2012
Issue of the American Organ Institute newsletter; advertisement for concert by Ken Double and Skip Stine; "Principal Chorus" update announcing the creation of the American Theatre Organ Library at AOI based on the ATOS archives, congratulating students ...
American Organ Institute
core  

Radiation dose from digital breast tomosynthesis screening - A comparison with full field digital mammography. [PDF]

open access: yes, 2020
OBJECTIVES: To compare Mean Glandular Dose (MGD) and effective dose from digital breast tomosynthesis (DBT) screening with that from full field digital mammography (FFDM) screening.

core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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