Results 101 to 110 of about 543,949 (257)

Absorbed Organ Doses and Effective Doses in Intraoral Radiography of Left Upper Molar of Adult Patient: A Computational Study

Oral
Objectives. To investigate effective doses and relevant absorbed organ doses for typical intraoral radiographic imaging procedures in adult patients. Variations of relevant absorbed organ doses and effective doses due to changes in imaging parameters and
Dario Faj, Zoran Mirkov, Ivor Dukić, Hrvoje Brkić   +3 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

NCIRF: an organ dose calculator for patients undergoing radiography and fluoroscopy. [PDF]

Biomed Phys Eng Express, 2023
Lee C, Lee C, Yeom YS, Shin J, Streitmatter SW, Kitahara CM.   +5 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Internal organ dose rate conversion coefficients of Japanese macaques to 134Cs,137Cs and 131I†. [PDF]

J Radiat Res, 2023
Takamura Y, Kajimoto T, Tanaka K, Yamamoto T, Suzuki M, Inaba Y, Chida K, Fukumoto M, Rangacharyulu C, Endo S.   +9 more
europepmc   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Evaluation of Absorbed Dose from Common Radiology Examinations in Yasuj, Iran, Using Experimental Measurement and Monte Carlo Calculations

مجله دانشکده پزشکی اصفهان, 2016
Background: The aim of this study was to investigate organ absorbed dose for the patients undergoing routine x-ray imaging procedures in hospitals under the control of Yasuj University of Medical Sciences, Iran, in year 2014 using experimental ...
Daryoush Shahbazi-Gahrouei, Mohammad Reza Abdi, Aghdas Paknejad, Milad Baradaran-Ghahfarokhi   +3 more
doaj  

Acute diquat poisoning in children: a single-center retrospective observational study

Frontiers in Pediatrics
BackgroundAcute diquat poisoning can cause multi-organ dysfunction and even death. The dose-effect relationship and multi-organ injury patterns of diquat poisoning in children remain unclear.ObjectiveThis study analyzed 58 pediatric cases to ...
Mingxia Li, Peisheng Jia, Erhu Wei
doaj   +1 more source