Results 61 to 70 of about 517,318 (306)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground The long‐term effects of physical activity (PA) variability and cumulative PA (CPA) from young adulthood on cardiac remodeling remain controversial, and it is unclear whether these effects resemble those observed in elite athletes.
Shunyi Li +12 more
doaj +1 more source
Quick sepsis-related organ failure assessment in identifying clinical deterioration in patients with COVID-19 [PDF]
, 2023 Luiz Felipe Sales Maurício +4 more
openalex +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Journal of Extracellular VesiclesDuring fibrogenesis, certain negative feedback loops are elicited to restrain persistent and hyperactive fibrotic responses. Activated fibroblasts have been found to acquire anti‐fibrotic phenotypes.
Shichao Li +7 more
doaj +1 more source
Epidemiology of acute kidney injury in hospitalized pregnant women in China
BMC Nephrology, 2019 Background Epidemiologic data of acute kidney injury (AKI) during pregnancy is lacking in China. This study aims to determine the effect of pregnancy on the risk of AKI among hospitalized women of childbearing age, and to describe the incidence, risk ...
Diankun Liu +8 more
doaj +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Clinical and Translational MedicineIntroduction Heart failure with preserved ejection fraction (HFpEF) is a complex condition characterized by metabolic dysfunction and myocardial lipotoxicity.
Hao Zhang +10 more
doaj +1 more source
Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey +2 more
wiley +1 more source
Essential amino acids to treat sarcopenia in patients with COPD?
Monaldi Archives for Chest Disease, 2016 -
E.P.A. Rutten, M.A. Spruit
doaj +1 more source