Results 91 to 100 of about 1,992,155 (390)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Structure-aware registration network for liver DCE-CT images [PDF]

open access: yesarXiv, 2023
Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with complex spatial motion induced by respiration brings great challenge to existing intensity-based registration ...
arxiv  

Endothelial cell protection against ischemia/reperfusion injury by lecithinized superoxide dismutase [PDF]

open access: yes, 2001
Endothelial cell protection against ischemia/reperfusion injury by lecithinized superoxide dismutase.BackgroundOrgans used for transplantation may experience long periods of cold ischemic preservation and consequently oxygen free radical-mediated damage ...
Koo, Dicken D.H.   +7 more
core   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1170-1187, April 2025.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies   +9 more
wiley   +1 more source

The role of oxygenation in kidney and liver machine perfusion

open access: yesТрансплантология (Москва), 2023
Background. Organ transplantation is the optimal decision for patients in the end stage of many diseases. Certain conditions are required for the transportation and preservation of a donor organ after explantation, including factors such as temperature ...
M. S. Novruzbekov   +8 more
doaj   +1 more source

Isolated Organ Perfusion: Physiology and Application [PDF]

open access: yes, 1969
Isolated organ perfusion provides us with an excellent tool for investigating the physiology and the function of a variety of individual organs. It enables us to explore these organs, their pharmacologic reactions, their ability to withstand various ...
Gayle, William E., Jr.
core   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Organ preservation in splenic abscess [PDF]

open access: yesMedical Journal Armed Forces India, 2014
10-year-old male child, with no known co-morbidities anda normal developmental history, presented with history offever for 10 days and pain in abdomen for 8 days. The onset ofboth symptoms was insidious. The fever was moderate tohigh grade and not associated with rigors or chills.
M. Talreja   +4 more
openaire   +3 more sources

Current strategies to prevent ishcemia reperfusion injury in organ transplantation [PDF]

open access: yes, 2020
Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by ...
Rumbo, Martín, Stringa, Pablo Luis
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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