Privacy-Preserving Dataset Combination [PDF]
Access to diverse, high-quality datasets is crucial for machine learning model performance, yet data sharing remains limited by privacy concerns and competitive interests, particularly in regulated domains like healthcare. This dynamic especially disadvantages smaller organizations that lack resources to purchase data or negotiate favorable sharing ...
arxiv
Review and prospect of neoadjuvant chemoradiotherapy combined with immunotherapy in locally advanced rectal cancer [PDF]
For locally advanced rectal cancer (LARC), the standard treatment of neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) leaded to limited tumor regression grade and organ preservation rate, and didn’t decrease the rate of ...
WANG Yaqi, XIA Fan, ZHANG Zhen
doaj +1 more source
The cold chain delivery of organs for transplantation: from research laboratories and individual enthusiasts to pan-global networks in 50 years [PDF]
It is some 50 years since the first published reports appeared of ex vivo preservation of organs for transplantation. Over the intervening decades, organ preservation strategies have become one essential component of world-wide clinical transplant ...
Fuller, Barry J, Green, Colin C
core
Thyroid Hormone as a Method of Reducing Damage to Donor Hearts after Circulatory Arrest [PDF]
There is a chronic lack of donor hearts to meet the need for heart transplant both in the US and worldwide. Further, the use of available hearts is limited by the short period between collection and implantation during which the heart can be safely ...
Adams, William P.
core +1 more source
Abstract The NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of several noncommunicable diseases. It induces caspase‐1 activation and the downstream substrates involved with the processing and secretion of the pro‐inflammatory cytokines IL‐1β ...
Yucen Zou+6 more
wiley +1 more source
Perfusion bioreactor for liver bioengineering [PDF]
End-stage organ failure has grown to become one of the key challenges for the medical community because of the high number of patients in waiting list for a transplant and the severe shortage of suitable organ donors.
Cancio Villalonga, David
core
Dopaminergic therapy disrupts decision‐making in impulsive‐compulsive Parkinsonian patients
Abstract Impulsive‐compulsive behaviors (ICB) are common non‐motor symptoms of Parkinson's disease (PD) often associated with dopaminergic drugs (DD) therapy. We investigated the acute effects of DD on decision‐making in PD patients with ICB (ICB+) and without it (ICB−), and in healthy controls (HC).
Fabio Taddeini+12 more
wiley +1 more source
Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy
Abstract Objectives We aim to investigate cognitive phenotype distribution and MRI correlates across pediatric‐, elderly‐, and adult‐onset MS patients as a function of disease duration. Methods In this cross‐sectional study, we enrolled 1262 MS patients and 238 healthy controls, with neurological and cognitive assessments.
Ermelinda De Meo+23 more
wiley +1 more source
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita+7 more
wiley +1 more source
THE PRESERVATION OF ORGANIZED URINARY SEDIMENTS [PDF]
n ...
openaire +1 more source