Results 1 to 10 of about 463,068 (88)

Candida Contamination in Kidney and Liver Organ Preservation Solution: Does It Matter? [PDF]

open access: yesJournal of Clinical Medicine, 2021
Introduction: Fungal infections remain a major challenge affecting outcomes after kidney (KT) and liver transplantation (LT). Methods: In this retrospective single center study, the incidence of Candida contamination in renal and hepatic graft ...
Sabrina Stern   +4 more
semanticscholar   +6 more sources

Evaluation of the presence of microorganisms in solid-organ preservation solution. [PDF]

open access: yesBrazilian Journal of Infectious Diseases, 2011
OBJECTIVE To assess the presence of microorganism contamination in the preservation solution for transplant organs (kidney/pancreas). METHOD Between August 2007 and March 2008, 136 samples of preservation solution were studied prior to graft ...
A. Mattana   +5 more
semanticscholar   +11 more sources

Effect of University of Wisconsin organ-preservation solution on haemorheology [PDF]

open access: yesTransplant International, 2004
In conventional cold-storage organ preservation, the donor organ is flushed with University of Wisconsin (UW) solution at 0-4 degrees C. The initial flush is used to wash out blood from the microcirculation to allow optimal preservation with the UW solution. The component hydroxyethyl starch (HES) of UW is known to cause relatively high viscosity and a
A. Plaats   +6 more
semanticscholar   +4 more sources

Organ preservation using a photosynthetic solution [PDF]

open access: yesTransplantation Research, 2012
BackgroundOrgans harvested from a body lapsing into circulatory deficit are exposed to low O2/high CO2, and reach a critical point where original functionality after transplantation is unlikely.
I. Yamaoka   +3 more
semanticscholar   +4 more sources

James Southard, PhD, Professor of Surgery (Emeritus), Pioneer in Organ Preservation, Co-inventor, UW Organ Preservation Solution.

open access: yesTransplantation, 2020
JS: I had finished a postdoctoral fellowship at the Enzyme Institute, University of Wisconsin, and was working there in a research position. I knew little about opportunities in organ preservation. Dr Belzer had recently (1974) become Chair of Surgery at
J. Southard
semanticscholar   +1 more source

Portable hypothermic oxygenated machine perfusion for organ preservation in liver transplantation: A randomized, open-label, clinical trial

open access: yesHepatology, 2023
Background and Aims: In liver transplantation, cold preservation induces ischemia, resulting in significant reperfusion injury. Hypothermic oxygenated machine perfusion (HMP-O2) has shown benefits compared to static cold storage (SCS) by limiting ...
G. Panayotova   +17 more
semanticscholar   +1 more source

Significant Improvement in Rat Kidney Cold Storage Using UW Organ Preservation Solution Supplemented With the Immediate-Acting PrC-210 Free Radical Scavenger

open access: yesTransplantation Direct, 2020
Background. Ischemia-reperfusion injury, including injury from warm- and cold-ischemia (CI) organ storage, remains a significant problem for all solid organ transplants.
B. Verhoven   +6 more
semanticscholar   +1 more source

Evaluation of the efficacy of HEMO2life®, a marine OXYgen carrier for Organ Preservation (OxyOp2) in renal transplantation: study protocol for a multicenter randomized trial

open access: yesTrials, 2023
Background Preventing ischemia‒reperfusion injury (IRI) is a major issue in kidney transplantation, particularly for transplant recipients receiving a kidney from extended criteria donors (ECD). The main consequence of IRI is delayed graft function (DGF).
Y. Le Meur   +13 more
semanticscholar   +1 more source

Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it, creating an extreme dependency on external supply. In contrast, microalgae are photosynthetic microorganisms, therefore, they are able to produce oxygen as plant cells
Valentina Veloso-Giménez   +10 more
semanticscholar   +1 more source

The Effect of Antioxidant Added to Preservation Solution on the Protection of Kidneys before Transplantation

open access: yesInternational Journal of Molecular Sciences, 2022
Ischemia–reperfusion injury is a key clinical problem of transplantology. Current achievements in optimizing organ rinse solutions and storage techniques have significantly influenced the degree of graft damage and its survival after transplantation.
A. Ostróżka-Cieślik
semanticscholar   +1 more source

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