Results 261 to 270 of about 119,972 (311)

Organ preservation solutions impair deformability of erythrocytes in vitro

Transplantation Proceedings, 2003
Microcirculatory disturbances are observed frequently after restoration of the circulation in transplanted organ. The exact mechanisms responsible for impaired microcirculation during reperfusion are unknown. Erythrocyte deformability is an important factor maintaining the microcirculation.
B, Chmiel, L, Cierpka
openaire   +2 more sources

Organ-Specific Solutions and Strategies for the Intestinal Preservation

International Reviews of Immunology, 2013
Among the intraabdominal organs, the intestine is the most susceptible to storage injury and as a consequence its safe cold ischemic time in the clinic is restricted to below 10 hours. The current practice for the intestinal preservation (IP) consists of an in-situ vascular flush with iced University of Wisconsin or Histidine-Tryptophan-Ketoglutarate ...
Mihai, Oltean, Thomas A, Churchill
openaire   +2 more sources

Inherent toxicity of organ preservation solutions to cultured hepatocytes

Cryobiology, 2008
Organ preservation solutions have been designed to protect grafts against the injury inflicted by cold ischemia. However, toxicity of University of Wisconsin (UW) solution during rewarming has been reported. Therefore, we here assessed the toxicity of UW, histidine-tryptophan-ketoglutarate (HTK), Euro-Collins, histidine-lactobionate (HL), sodium ...
Ursula, Rauen, Herbert, de Groot
openaire   +2 more sources

Drug Development Considerations for Additives to Organ Preservation Solutions

Transplantation
The addition of a novel therapeutic agent to an organ preservation solution has the potential to address unmet needs in organ transplantation and enhance outcomes for transplant recipients. However, the development expectations for novel therapeutic agents in this context are unclear because of limited precedence and published regulatory guidance ...
Matthew, O'Brien Laramy, Jamie, Robinson, C J, Venkatramani, Stephanie, Horn, Carine, Steiner, Yoen-Ju, Son   +5 more
openaire   +2 more sources

SOLUTIONS FOR ORGAN PRESERVATION

The Lancet, 1970
K C, Calman, P R, Bell, S G, Macpherson, R F, Wood, R O, Quin   +4 more
openaire   +2 more sources

ORGAN PRESERVATION BY COLLINS' SOLUTION

The Lancet, 1971
G M, Abouna, R, Hurwitz, B, Serrou
openaire   +2 more sources

Endothelial cell preservation using organ storage solutions.

Transplantation, 1992
The development of organ preservation solutions has been primarily accomplished in whole organ animal models. This study examines the toxicity of commonly used organ preservation solutions on endothelial cells in vitro. Primary human umbilical-vein endothelial cell cultures were incubated at 4 degrees C in solutions of 0.9% saline (NS), EuroCollins ...
W A, Killinger, D B, Dorofi, B A, Keagy, G, Johnson   +3 more
openaire   +1 more source

Production of high‐quality islets from goettingen minipigs: Choice of organ preservation solution, donor pool, and optimal cold ischemia time

Xenotransplantation, 2017
A. Steffen, T. Kiss, Janine Schmid, Undine Schubert, S. Heinke, Susann Lehmann, S. Bornstein, B. Ludwig, S. Ludwig   +8 more
semanticscholar   +1 more source

Current organ preservation solutions for liver preservation: experimental comparison

Transplantation Proceedings, 2000
R H, Tolba, S, Akbar, U, Puetz, T, Minor
openaire   +2 more sources

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca-A Cancer Journal for Clinicians, 2021
Kyle Wang
exaly