Results 21 to 30 of about 463,068 (88)
Cell & Bioscience, 2018 Organ preservation solutions are designed to minimize organ damage during transplantation. A novel preservation solution, WMO-II, was developed to have a low viscosity and to improve microvasculature perfusion for kidneys.
Sheng Wang +12 more
semanticscholar +1 more source
Pharmaceuticals, 2021 Vascular ischemia/reperfusion injury (IRI) in patients undergoing coronary artery bypass grafting can result in graft failure and the need for repeat revascularization procedures.
S. Korkmaz‐Icöz +9 more
semanticscholar +1 more source
Tips for optimizing organ preservation solutions
Acta Biochimica Polonica, 2018 Organ injury during ischemia is one of the clinical problems of today's transplantation. It occurs during warm ischemia time (WIT) when the blood flow is cut off and during cold ischemia when a graft is chilled in situ until the circulation is restored to the recipient organism.
Barbara Dolińska +2 more
openaire +4 more sources
Original and generic preservation solutions in organ transplantation. A new paradigm? [PDF]
Acta Cirúrgica Brasileira, 2020 Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation
Joan Roselló-Catafau +5 more
openaire +7 more sources
PLoS ONE, 2021 Organs from donors after controlled circulatory death (DCD III) exhibit a higher risk for graft dysfunction due to an initial period of warm ischemia.
D. D. De Paep +7 more
semanticscholar +1 more source
Development of New Organ Preservation Solutions in Kyoto University [PDF]
Yonsei Medical Journal, 2004 Although lung transplantation (LTx) has been established as a therapeutic approach for end-stage respiratory failure, several problems remain to be solved. In addition to the serious problem of donor shortage, primary graft failure, which is mostly caused by ischemia-reperfusion injury, a serious problem, and represents one of the most frequent causes ...
Fengshi Chen +2 more
openaire +2 more sources
A single solution for multiple organ procurement and preservation
Transplant International, 2005 Two or three different solutions may be used to preserve thoracic and abdominal organs during a single procurement. The aim of this prospective, multi-center, noncomparative study was to evaluate the safety and efficacy of Celsior (study solution, solution S) as a flushing and cold storage solution for both thoracic and abdominal organs. Between August
Didier Noury +6 more
openaire +3 more sources
American Journal of Transplantation, 2020 The medical device M101 is an extracellular hemoglobin featuring high oxygen‐carrying capabilities. Preclinical studies demonstrated its safety as an additive to organ preservation solutions and its beneficial effect on ischemia/reperfusion injuries ...
Y. Le Meur +12 more
semanticscholar +1 more source
Clinical Proteomics, 2023 Purpose The organ perfusion solution (perfusate), collected at clinically and temporally significant stages of the organ preservation and transplantation process, provides a valuable insight into the biological status of an organ over time and prior to ...
Corinna Snashall +5 more
semanticscholar +1 more source
Current Opinion in Organ Transplantation, 2018 To provide an understanding of the scientific principles, which underpinned the development of organ preservation solutions, and to bring into context new strategies and challenges for solution development against the background of changing preservation technologies and expanded criteria donor access.Improvements in organ preservation solutions ...
Fuller, B, Froghi, F, Davidson, B
openaire +4 more sources