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Solution development in organ preservation: The University of Wisconsin perspective
Transplantation Reviews, 1999Transplantation of solid organs, although dependent upon many factors, is particularly dependent upon successful organ preservation. The primary goal of organ preservation should be to maximize utilization of donor organs, and prevent organ wastage while, at the same time, providing excellent function.
Robert M. Hoffmann +2 more
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Perspectives on Abdominal Organ Preservation Solutions: A Comparative Literature Review
Progress in Transplantation, 2013Various preservation solutions are used for kidney, liver, pancreas, small intestine, and multiorgan recoveries and transplants. The effectiveness of these solutions, primarily measured by ability to preserve the organ and graft survival, was analyzed. The 2 most common solutions used for intra-abdominal organs are University of Wisconsin Solution (UW)
Marcia R. Voigt, Ginger T. DeLario
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IMPROVED PRESERVATION SOLUTIONS FOR ORGAN STORAGE
Transplantation, 1999Organ cold storage times may be extended by modifications to organ preservation solutions.Three preservation solutions were investigated for their ability to maintain viable hepatic bioenergetics in stored pig livers: modified University of Wisconsin (mUW); mUW+adenosine (1.34 g/L), and mUW+ iloprost (10(-8)mol/L), a prostacyclin analogue.
Duncan P. Moore +5 more
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Organ preservation: Experience with University of Wisconsin solution and plans for the future
Clinical Transplantation, 1990Transplantation of organs continues to be a primary therapeutic modality for treatment of end‐stage organ disease, and 1‐year graft survival rates show increasing improvements for most organs. A number of transplant centers show 1‐yr graft survival rates approaching 90% or more for the kidney, liver and pancreas.
F O, Belzer +7 more
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Bacterial contamination of organ graft preservation solution and infection after transplantation
Transplant Infectious Disease, 2011M. Sauget, S. Verdy, C. Slekovec, X. Bertrand, D. Talon. Bacterial contamination of organ graft preservation solution and infection after transplantation. Transpl Infect Dis 2011: 13: 331–334. All rights reservedAbstract: Infectious complications represent a major cause of morbidity and mortality in patients with organ transplantation.
Sauget, M. +4 more
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ORGAN PRESERVATION BY COLLINS' SOLUTION
The Lancet, 1971Richard Hurwitz +2 more
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Drug Development Considerations for Additives to Organ Preservation Solutions
TransplantationThe addition of a novel therapeutic agent to an organ preservation solution has the potential to address unmet needs in organ transplantation and enhance outcomes for transplant recipients. However, the development expectations for novel therapeutic agents in this context are unclear because of limited precedence and published regulatory guidance ...
Matthew, O'Brien Laramy +5 more
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Organ preservation with the UW solution
Cryobiology, 1988Hans W. Sollinger +4 more
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