Results 141 to 150 of about 13,374,903 (323)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Windlines. Volume 7, number 1 (Winter 2013)

open access: yes, 2013
Issue of the American Organ Institute newsletter; "The Tradition Continues" update on student achievements in the Longwood Gardens International Organ Competition, the Ruth and Clarence Mader Scholarship Fund, and the Cherine Troxel Organ Scholarship ...
American Organ Institute
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Organ in ensemble : the dearth of Australian chamber music and concertos for organ

open access: yes, 2016
This article surveys and tallies Australian chamber works and concerti for organ, and their composers; and it attempts to grasp at reasons so few of these works ...
McKern, Brett (R18958)
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Windlines. Volume 6, number 1 (Spring 2013)

open access: yes, 2013
Issue of the American Organ Institute newsletter; "Message from the Director" includes update on student success in competitions, restoration of the Moller Opus 5819, and progress in the archives; "Pedals, Pipes & Pizza!" event review for community piano
American Organ Institute
core  

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

The Relationship of the Lower Ribcage with Liver and Gut Size: Implications for Paleoanthropology

open access: yesHumans
Organ–skeleton relationships are understudied in biological anthropology. The torso skeleton is often used to infer the organ size and evolution in hominins; ribcage “types”, in particular, are used to infer the abdominal organ size in hominins.
Jeanelle Uy   +2 more
doaj   +1 more source

Windlines. Volume 5, number 3 (Summer 2012)

open access: yes, 2012
Issue of the American Organ Institute newsletter; "Message from the Director" relating the rise of AOI to the rise of the University of Oklahoma under David Boren's leadership; AOI events for the fall; "Fanfare" column congratulating Adam Pajan, Chris ...
American Organ Institute
core  

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