Results 41 to 50 of about 465,843 (360)

Challenges in Organ Transplantation [PDF]

open access: yesRambam Maimonides Medical Journal, 2011
Organ transplantation has progressed tremendously with improvements in surgical methods, organ preservation, and pharmaco-immunologic therapies and has become a critical pathway in the management of severe organ failure worldwide. The major sources of organs are deceased donors after brain death; however, a substantial number of organs come from live ...
openaire   +3 more sources

Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal

open access: yesResearch, 2023
Background: Hepatic ischemia-reperfusion injury (HIRI) stands as an unavoidable complication arising from liver surgery, profoundly intertwined with its prognosis.
Kang Xia   +8 more
doaj   +1 more source

Multi-Task Learning for Post-transplant Cause of Death Analysis: A Case Study on Liver Transplant [PDF]

open access: yesarXiv, 2023
Organ transplant is the essential treatment method for some end-stage diseases, such as liver failure. Analyzing the post-transplant cause of death (CoD) after organ transplant provides a powerful tool for clinical decision making, including personalized treatment and organ allocation. However, traditional methods like Model for End-stage Liver Disease
arxiv  

Fairly Predicting Graft Failure in Liver Transplant for Organ Assigning [PDF]

open access: yesarXiv, 2023
Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making organ distribution decisions. However, it ignores post-transplant outcomes and organ/donor features.
arxiv  

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Preparation and characterization of small-diameter decellularized scaffolds for vascular tissue engineering in an animal model

open access: yesBioMedical Engineering OnLine, 2017
Background The development of a suitable extracellular matrix (ECM) scaffold is the first step in vascular tissue engineering (VTE). Synthetic vascular grafts are available as an alternative to autologous vessels in large-diameter arteries (>8 mm) and ...
Shuangyue Xu   +11 more
doaj   +1 more source

Impact of para aortic lymph node removal on survival following resection for pancreatic adenocarcinoma

open access: yesBMC Surgery, 2023
Introduction For PDAC patients undergoing resection, it remains unclear whether metastases to the paraaortic lymph nodes (PALN+) have any prognostic significance and whether metastases should lead to the operation not being carried out. Our hypothesis is
Martin Sillesen   +7 more
doaj   +1 more source

The co-development of liver and kidney transplantation (1955-1967) [PDF]

open access: yes, 2003
Between 1955 and the end of 1967, the framework of clinical transplantation that exists today was established in a small number of centers in continental Europe, Great Britain, and the United States.
Starzl, TE
core  

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Organ Transplantation from the Deceased [PDF]

open access: yes, 1968
Loening in a Parks class filled with students.
Guttentag, Otto E.
core   +2 more sources

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