Results 81 to 90 of about 1,167,376 (291)

LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy

Journal for ImmunoTherapy of Cancer
Background Tumor-infiltrating T cells enter an exhausted or dysfunctional state, which limits antitumor immunity. Among exhausted T cells, a subset of cells with features of progenitor or stem-like cells has been identified as TCF1+ CD8+ T cells that ...
Zhishui Chen, Gang Chen, Li Chen, Xiangli Zhao, Lingjuan Sun, Zhibo Ma, Xiaosheng Tan, Yuhao Tu, Jingzeng Wang, Peixiang Lan   +9 more
doaj   +1 more source

Role of the human beta-herpesviruses in organ allograft rejection following transplantation. [PDF]

, 2005
In previous prospective studies conducted in our department, PCR was used to detect the three ({dollar}-herpesviruses, human cytomegalovirus (HCMV), and human herpesviruses 6 and 7 (HHV-6 and HHV-7) in the blood of solid organ transplant patients.
Li, Y.T., Li, Yingting
core  

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Interpretable SVM Model for Predicting CMV Infection in Seropositive Kidney Transplant Recipients: A Single-Center Retrospective Study

Infection and Drug Resistance
Guangli Zhong,1 Yujie Tang,1 Runtao Feng,1 Xujun Xu,1 Ya Zhang,1 Junpeng Wang,2 Song Zhou,1 Ming Zhao1 1Department of Organ Transplantation, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People’s Republic of China; 2Department of ...
Zhong G, Tang Y, Feng R, Xu X, Zhang Y, Wang J, Zhou S, Zhao M   +7 more
doaj  

Immunosuppressant nonadherence profile in kidney transplant recipients and the impact of medication adherence on transplant outcomes

Frontiers in Pharmacology
BackgroundDespite the fact that 1-year graft and recipient survival rates are above 90% in most transplant centers, improving long-term graft survival remains an important challenge.
Zou Zhi-yu, Zou Zhi-yu, Dai Lin-rui, Yu Chen-zhen, Chen Ren-jie, Yu Fei-hong, Chen Song, Chang Sheng, Zhang Wei-jie   +8 more
doaj   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

SIMULTANEOUS INFRARENAL AORTIC PROSTHESIS IMPLANTATION AND RENAL TRANSPLANTATION IN PATIENT ON PERITONEAL DIALYSIS

Вестник трансплантологии и искусственных органов, 2010
SIMULTANEOUS INFRARENAL AORTIC PROSTHESIS IMPLANTATION AND RENAL TRANSPLANTATION IN PATIENT ON PERITONEAL ...
A. V. Kolsanov, M. S. Mikhaylov, B. I. Yaremin, D. A. Chernovalov, A. A. Mironov   +4 more
doaj   +1 more source

Cyclosporine and organ transplantation

Cleveland Clinic Journal of Medicine, 1985
Cyclosporine is a potent new immunosuppressive agent which is now available for use in clinical transplantation. It has a unique mechanism of action, interfering primarily with the cell-mediated response to foreign antigens. Cyclosporine has been very effective in preventing early graft loss due to rejection and has resulted in improved graft survival ...
D. G. Vidt, A. W. Bakst, D. R. Steinmuller   +2 more
openaire   +2 more sources

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source