Results 1 to 10 of about 110,893 (161)
Applying systems-level spectral imaging and analysis to reveal the organelle interactome
Nature, 2017 The organization of the eukaryotic cell into discrete membrane-bound organelles allows for the separation of incompatible biochemical processes, but the activities of these organelles must be coordinated.
A. Valm +9 more
semanticscholar +3 more sources
Regulation of V-ATPase Activity and Organelle pH by Phosphatidylinositol Phosphate Lipids
Frontiers in Cell and Developmental Biology, 2020 Luminal pH and the distinctive distribution of phosphatidylinositol phosphate (PIP) lipids are central identifying features of organelles in all eukaryotic cells that are also critical for organelle function.
Subhrajit Banerjee, P. Kane
semanticscholar +3 more sources
Signal Transduction and Targeted Therapy, 2022 Cancer is a major threat to human health. Among various treatment methods, precision therapy has received significant attention since the inception, due to its ability to efficiently inhibit tumor growth, while curtailing common shortcomings from ...
Jingjing Yang +3 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 The autophagy protein ATG2, proposed to transfer bulk lipid from the endoplasmic reticulum (ER) during autophagosome biogenesis, interacts with ER residents TMEM41B and VMP1 and with ATG9, in Golgi-derived vesicles that initiate autophagosome formation ...
A. Ghanbarpour +3 more
semanticscholar +1 more source
Nucleic Acids Res., 2020 The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA).
S. Rath +31 more
semanticscholar +1 more source
A molecular pore spans the double membrane of the coronavirus replication organelle
Science, 2020 Viral RNA exported from the coronavirus replication organelle is likely to be mediated by a crown-shaped molecular pore. A gateway to the cytosol Coronaviruses transform host cell membranes into peculiar double-membrane vesicles that have long been ...
Georg Wolff +11 more
semanticscholar +1 more source
bioRxiv, 2020 Zoonotic coronavirus (CoV) infections, like those responsible for the current SARS-CoV-2 epidemic, cause grave international public health concern. In infected cells, the CoV RNA-synthesizing machinery associates with modified endoplasmic reticulum ...
E. Snijder +8 more
semanticscholar +1 more source
Autophagy, 2020 The structural integrity and functional stability of organelles are prerequisites for the viability and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the pathogenesis and progression of various diseases, such as ...
R. Yao, C. Ren, Z. Xia, Yong-ming Yao
semanticscholar +1 more source
GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes
Genome Biology, 2018 GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from whole genome sequencing data. It recruits organelle-associated reads using a modified “baiting and iterative mapping” approach, conducts de novo assembly, filters ...
Jianjun Jin +6 more
semanticscholar +1 more source