Results 1 to 10 of about 463,135 (398)
Regulation of V-ATPase Activity and Organelle pH by Phosphatidylinositol Phosphate Lipids
Frontiers in Cell and Developmental Biology, 2020 Luminal pH and the distinctive distribution of phosphatidylinositol phosphate (PIP) lipids are central identifying features of organelles in all eukaryotic cells that are also critical for organelle function.
Subhrajit Banerjee, Patricia M Kane
exaly +4 more sources
Applying systems-level spectral imaging and analysis to reveal the organelle interactome
Nature, 2017 The organization of the eukaryotic cell into discrete membrane-bound organelles allows for the separation of incompatible biochemical processes, but the activities of these organelles must be coordinated.
Sarah Cohen +2 more
exaly +2 more sources
Specific association of TBK1 with the trans-Golgi network following STING stimulation
Cell Structure and Function, 2022 Stimulator of interferon genes (STING) is essential for the type I interferon response induced by microbial DNA or self-DNA leaked from mitochondria/nuclei.
Haruka Kemmoku +3 more
doaj +1 more source
STING Operation at the ER/Golgi Interface
Frontiers in Immunology, 2021 DNA is present in the nucleus and mitochondria of eukaryotic cells. There are, however, certain instances in which DNA emerges in the cytosol. The two major sources of cytosolic DNA are self DNA that is leaked out from the nucleus or mitochondria, and ...
Tomohiko Taguchi +4 more
doaj +1 more source
Signal Transduction and Targeted Therapy, 2022 Cancer is a major threat to human health. Among various treatment methods, precision therapy has received significant attention since the inception, due to its ability to efficiently inhibit tumor growth, while curtailing common shortcomings from ...
Jingjing Yang +3 more
semanticscholar +1 more source
Plants, 2023 Protein phosphatase 2A (PP2A) is a heterotrimeric conserved serine/threonine phosphatase complex that includes catalytic, scaffolding, and regulatory subunits.
Ahmed Elshobaky +3 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 The autophagy protein ATG2, proposed to transfer bulk lipid from the endoplasmic reticulum (ER) during autophagosome biogenesis, interacts with ER residents TMEM41B and VMP1 and with ATG9, in Golgi-derived vesicles that initiate autophagosome formation ...
A. Ghanbarpour +3 more
semanticscholar +1 more source
Nucleic Acids Res., 2020 The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA).
S. Rath +31 more
semanticscholar +1 more source
CDK1 controls CHMP7-dependent nuclear envelope reformation
eLife, 2021 Through membrane sealing and disassembly of spindle microtubules, the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) machinery has emerged as a key player in the regeneration of a sealed nuclear envelope (NE) during mitotic exit, and in
Alberto T Gatta +5 more
doaj +1 more source