Results 1 to 10 of about 1,118,522 (291)
Emerging perspectives on the selective autophagy of melanosomes: melanophagy [PDF]
Experimental and Molecular MedicineMelanosomes are highly specialized organelles responsible for melanin synthesis, storage and transport in melanocytes, playing a central role in pigmentation and skin homeostasis.
Na Yeon Park +3 more
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Specific association of TBK1 with the trans-Golgi network following STING stimulation
Cell Structure and Function, 2022 Stimulator of interferon genes (STING) is essential for the type I interferon response induced by microbial DNA or self-DNA leaked from mitochondria/nuclei.
Haruka Kemmoku +3 more
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Current Protocols in Protein Science, 2006 AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre +3 more
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STING Operation at the ER/Golgi Interface
Frontiers in Immunology, 2021 DNA is present in the nucleus and mitochondria of eukaryotic cells. There are, however, certain instances in which DNA emerges in the cytosol. The two major sources of cytosolic DNA are self DNA that is leaked out from the nucleus or mitochondria, and ...
Tomohiko Taguchi +4 more
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Cell Structure and Function, 2019 In research on cell biology, organelles have been a major unit of such analyses. Researchers have assumed that the inside of an organelle is almost uniform in regards to its function, even though each organelle has multiple functions. However, we are now facing conundrums that cannot be resolved so long as we regard organelles as functionally uniform ...
Kanae Sasaki, Hiderou Yoshida
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Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions [PDF]
Frontiers in Cell and Developmental Biology, 2020 Retrograde transport from endosomes to the trans-Golgi network (TGN) diverts proteins and lipids away from lysosomal degradation. It is essential for maintaining cellular homeostasis and signaling. In recent years, significant advancements have been made in understanding this classical pathway, revealing new insights into multiple steps of vesicular ...
Yingfeng Tu +3 more
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CDK1 controls CHMP7-dependent nuclear envelope reformation
eLife, 2021 Through membrane sealing and disassembly of spindle microtubules, the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) machinery has emerged as a key player in the regeneration of a sealed nuclear envelope (NE) during mitotic exit, and in
Alberto T Gatta +5 more
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Plants, 2023 Protein phosphatase 2A (PP2A) is a heterotrimeric conserved serine/threonine phosphatase complex that includes catalytic, scaffolding, and regulatory subunits.
Ahmed Elshobaky +3 more
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Current Opinion in Cell Biology, 2018 Eukaryotic cells are organized into membrane-bound organelles. These organelles communicate with one another through vesicular trafficking pathways and membrane contact sites (MCSs). MCSs are sites of close apposition between two or more organelles that play diverse roles in the exchange of metabolites, lipids and proteins.
Sarah Cohen +2 more
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FEBS Open Bio, 2020 Transglutaminases are a family of enzymes that catalyse the cross‐linking of proteins by forming covalent bonds between lysine and glutamine residues in various polypeptides.
Rebeca Garcia Alvarez +5 more
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