Results 161 to 170 of about 1,118,522 (291)

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

A Straightforward Interpretation of Proximity Labeling through Direct Biotinylation Analysis

ACS Omega
Han Byeol Kim, Kwang-eun Kim
doaj   +1 more source

Advances and Applications of Spatial Proteomics: From Organellar Maps to Clinical Translation. [PDF]

Chembiochem
Bernardini C, Däther M, Traube FR.
europepmc   +1 more source

3P-289 Correlation between RNA editing sites on amino acid residues and protein three-dimensional structures in plant organelles(The 46th Annual Meeting of the Biophysical Society of Japan)

, 2008
Mitiko Gō, Kei Yura
openalex   +2 more sources

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles [PDF]

, 2016
Kyung‐Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M. Mitrea, Mohona Sarkar, Brian D. Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex, Brian A. Maxwell, Nam Chul Kim, Jamshid Temirov, Jennifer C. Moore, Regina-Maria Kolaitis, Timothy I. Shaw, Bing Bai, Junmin Peng, Richard W. Kriwacki, J. Paul Taylor   +19 more
openalex   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD. [PDF]

Front Cell Dev Biol
Liu Y, Wang Y, Zhou J, Li H, Liu C, Zhong B, Liu J, Liu L, Zhang L, Sun L.   +9 more
europepmc   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Assembly and comparative analysis of the complete mitochondrial and chloroplast genomes of the medicinal plant Vincetoxicum Pycnostelma. [PDF]

BMC Genomics
Han J, Tian B, Shan C, Ren L, Xie H, Zhou Y, Wu S, Zhao F, Zhu Y, Zhang Y.   +9 more
europepmc   +1 more source

The SARS-CoV-2 nucleocapsid protein associates with the replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

, 2021
Katharina M. Scherer, Luca Mascheroni, George Carnell, Lucia C. S. Wunderlich, Stanislaw Makarchuk, Marius Brockhoff, Ioanna Mela, Ana Fernández‐Villegas, Max Barysevich, Hazel Stewart, Maria Suau Sans, Charlotte George, Jacob R. Lamb, Gabriele S. Kaminski Schierle, Jonathan L. Heeney, Clemens F. Kaminski   +15 more
openalex   +1 more source