Results 161 to 170 of about 1,088,075 (297)

Organelle Genomes of <i>Nardostachys jatamansi</i> Offer New Perspectives into the Evolutionary Dynamics of Caprifoliaceae. [PDF]

Biology (Basel)
Xiong Y, Xiong Y, Yu Q, Ma X, Lei X.
europepmc   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Oatk: a de novo assembly tool for complex plant organelle genomes. [PDF]

Genome Biol
Zhou C, Brown M, Blaxter M, Darwin Tree of Life Project Consortium, McCarthy SA, Durbin R.   +5 more
europepmc   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Organelle abnormalities in Alzheimer's disease. [PDF]

Organelle
Gao J, Vicuna L, Wang X.
europepmc   +1 more source

Cancer-cell organelles [PDF]

, 1983
Dej Jones
openalex   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source

Significance of stereologically spatiotemporal cells in molecular medicine. [PDF]

Clin Transl Med
Liu X, Duan W, Qiu Y, Li R, Song Y, Wang X.   +5 more
europepmc   +1 more source

Lung Concentric Laminar Organelle

, 1974
Richard P. DiAugustine, W. H. Howell
openalex   +1 more source

Organelle relationships in cultured 3T3-L1 preadipocytes. [PDF]

, 1980
Alex B. Novikoff, Phyllis M. Novikoff, O M Rosen, C S Rubin   +3 more
openalex   +1 more source