Results 11 to 20 of about 463,135 (398)

Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Retrograde transport from endosomes to the trans-Golgi network (TGN) diverts proteins and lipids away from lysosomal degradation. It is essential for maintaining cellular homeostasis and signaling. In recent years, significant advancements have been made in understanding this classical pathway, revealing new insights into multiple steps of vesicular ...
Lin Zhao   +3 more
openaire   +4 more sources

Organelle Proteomics [PDF]

open access: yesCurrent Protocols in Protein Science, 2006
AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre   +3 more
openaire   +6 more sources

A molecular pore spans the double membrane of the coronavirus replication organelle

open access: yesScience, 2020
Viral RNA exported from the coronavirus replication organelle is likely to be mediated by a crown-shaped molecular pore. A gateway to the cytosol Coronaviruses transform host cell membranes into peculiar double-membrane vesicles that have long been ...
Georg Wolff   +11 more
semanticscholar   +1 more source

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

open access: yesbioRxiv, 2020
Zoonotic coronavirus (CoV) infections, like those responsible for the current SARS-CoV-2 epidemic, cause grave international public health concern. In infected cells, the CoV RNA-synthesizing machinery associates with modified endoplasmic reticulum ...
E. Snijder   +8 more
semanticscholar   +1 more source

Characterisation of a novel cold‐adapted calcium‐activated transglutaminase: implications for medicine and food processing

open access: yesFEBS Open Bio, 2020
Transglutaminases are a family of enzymes that catalyse the cross‐linking of proteins by forming covalent bonds between lysine and glutamine residues in various polypeptides.
Rebeca Garcia Alvarez   +5 more
doaj   +1 more source

Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles

open access: yesAutophagy, 2020
The structural integrity and functional stability of organelles are prerequisites for the viability and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the pathogenesis and progression of various diseases, such as ...
R. Yao, C. Ren, Z. Xia, Yong-ming Yao
semanticscholar   +1 more source

The Crucial Roles of Phospholipids in Aging and Lifespan Regulation

open access: yesFrontiers in Physiology, 2021
Phospholipids are major membrane lipids that consist of lipid bilayers. This basic cellular structure acts as a barrier to protect the cell against various environmental insults and more importantly, enables multiple cellular processes to occur in ...
Yucan Dai, Haiqing Tang, Shanshan Pang
doaj   +1 more source

Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. [PDF]

open access: yes, 2018
Cellular differentiation involves remodeling cellular architecture to transform one cell type to another. By investigating mitochondrial dynamics during meiotic differentiation in budding yeast, we sought to understand how organelle morphogenesis is ...
Berchowitz, Luke   +5 more
core   +2 more sources

GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

open access: yesGenome Biology, 2018
GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from whole genome sequencing data. It recruits organelle-associated reads using a modified “baiting and iterative mapping” approach, conducts de novo assembly, filters ...
Jianjun Jin   +6 more
semanticscholar   +1 more source

Organelle by organelle [PDF]

open access: yesNature, 1975
The Cell in Medical Science. Vol. 1: The Cell and Its Organelles. Pp. xiii + 366. £7.80; $20.25. Vol. 2. Cellular Genetics, Development and Cellular Specialization. Pp. xvii + 597. £11.30; $29.25. Edited by F. Beck and J. B. Lloyd. (Academic: London and New York, January 1975.)
openaire   +2 more sources

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