Results 11 to 20 of about 1,088,075 (297)

Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions [PDF]

Frontiers in Cell and Developmental Biology, 2020
Retrograde transport from endosomes to the trans-Golgi network (TGN) diverts proteins and lipids away from lysosomal degradation. It is essential for maintaining cellular homeostasis and signaling. In recent years, significant advancements have been made in understanding this classical pathway, revealing new insights into multiple steps of vesicular ...
Lin Zhao, Daniel D. Billadeau, Da Jia, Yingfeng Tu   +3 more
openaire   +4 more sources

Specific association of TBK1 with the trans-Golgi network following STING stimulation

Cell Structure and Function, 2022
Stimulator of interferon genes (STING) is essential for the type I interferon response induced by microbial DNA or self-DNA leaked from mitochondria/nuclei.
Haruka Kemmoku, Yoshihiko Kuchitsu, Kojiro Mukai, Tomohiko Taguchi   +3 more
doaj   +1 more source

STING Operation at the ER/Golgi Interface

Frontiers in Immunology, 2021
DNA is present in the nucleus and mitochondria of eukaryotic cells. There are, however, certain instances in which DNA emerges in the cytosol. The two major sources of cytosolic DNA are self DNA that is leaked out from the nucleus or mitochondria, and ...
Tomohiko Taguchi, Tomohiko Taguchi, Kojiro Mukai, Eiko Takaya, Ruri Shindo   +4 more
doaj   +1 more source

Organelle Proteomics [PDF]

Current Protocols in Protein Science, 2006
AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre, Chevallet, Mireille, Luche, Sylvie, Rabilloud, Thierry   +3 more
openaire   +6 more sources

Protein–Protein Interactions and Quantitative Phosphoproteomic Analysis Reveal Potential Mitochondrial Substrates of Protein Phosphatase 2A-B’ζ Holoenzyme

Plants, 2023
Protein phosphatase 2A (PP2A) is a heterotrimeric conserved serine/threonine phosphatase complex that includes catalytic, scaffolding, and regulatory subunits.
Ahmed Elshobaky, Cathrine Lillo, Kristian Persson Hodén, Amr R. A. Kataya   +3 more
doaj   +1 more source

CDK1 controls CHMP7-dependent nuclear envelope reformation

eLife, 2021
Through membrane sealing and disassembly of spindle microtubules, the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) machinery has emerged as a key player in the regeneration of a sealed nuclear envelope (NE) during mitotic exit, and in
Alberto T Gatta, Yolanda Olmos, Caroline L Stoten, Qu Chen, Peter B Rosenthal, Jeremy G Carlton   +5 more
doaj   +1 more source

Characterisation of a novel cold‐adapted calcium‐activated transglutaminase: implications for medicine and food processing

FEBS Open Bio, 2020
Transglutaminases are a family of enzymes that catalyse the cross‐linking of proteins by forming covalent bonds between lysine and glutamine residues in various polypeptides.
Rebeca Garcia Alvarez, Pralav Karki, Ida Elise Langleite, Ragna‐Johanne Bakksjø, Lutz Andreas Eichacker, Clemens Furnes   +5 more
doaj   +1 more source

The Complete Mitochondrial Genome of a Neglected Breed, the Peruvian Creole Cattle (Bos taurus), and Its Phylogenetic Analysis

Data, 2022
Cattle spread throughout the American continent during the colonization years, originating creole breeds that adapted to a wide range of climate conditions.
Carlos I. Arbizu, Rubén D. Ferro-Mauricio, Julio C. Chávez-Galarza, Héctor V. Vásquez, Jorge L. Maicelo, Carlos Poemape, Jhony Gonzales, Carlos Quilcate, Flor-Anita Corredor   +8 more
doaj   +1 more source

Organelle by organelle [PDF]

Nature, 1975
The Cell in Medical Science. Vol. 1: The Cell and Its Organelles. Pp. xiii + 366. £7.80; $20.25. Vol. 2. Cellular Genetics, Development and Cellular Specialization. Pp. xvii + 597. £11.30; $29.25. Edited by F. Beck and J. B. Lloyd. (Academic: London and New York, January 1975.)
openaire   +2 more sources

Chaperones and Proteostasis: Role in Parkinson’s Disease

Diseases, 2020
Proper folding to attain a defined three-dimensional structure is a prerequisite for the functionality of a protein. Improper folding that eventually leads to formation of protein aggregates is a hallmark of several neurodegenerative disorders.
Neha Joshi, Atchaya Raveendran, Shirisha Nagotu   +2 more
doaj   +1 more source