Results 261 to 270 of about 1,088,075 (297)

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
wiley   +1 more source

Visualization of lysosomal membrane proteins by cryo electron tomography. [PDF]

Nat Commun
McVeigh BM, De Jesús-Pérez JJ, Siepe DH, Gogoi P, Mageswaran SK, Kalocsay M, Mihelc EM, Moiseenkova-Bell VY.   +7 more
europepmc   +1 more source

A 23-gene multi-omics signature predicts prognosis and treatment response in non-small cell lung cancer. [PDF]

Discov Oncol
Zhang Y, Wang S, Chen X, Zhang G, Wang Y, Liu X.   +5 more
europepmc   +1 more source

Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases: Exploring How Flawed Ribosome Recycling Factors Impact Ribosome Metabolism and Organelle Homeostasis, Leading to Human Diseases. [PDF]

Bioessays
Tahmasebinia F, Wu Z.
europepmc   +1 more source

The genome of Chenopodium ficifolium: developing genetic resources and a diploid model system for allotetraploid quinoa. [PDF]

G3 (Bethesda)
Ludwig CD, Maughan PJ, Jellen EN, Davis TM.   +3 more
europepmc   +1 more source

TurboID-based mapping of organelle membrane protein interactomes with digitonin-permeabilization. [PDF]

Biophys Rep
Sun Y, Yang L, Zhang J, Tian P, Chen S, Fang L, Hong Z.   +6 more
europepmc   +1 more source

Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement. [PDF]

Front Pharmacol
Tao J, Yuan Z, Zhou M.
europepmc   +1 more source