Results 271 to 280 of about 1,088,075 (297)
Characterisation of LAMP1- and LAMP2A-positive organelles in neurons
Abouward R +9 more
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New England Journal of Medicine, 1972 WE seem to be living through the biologic revolution, so far anyway, without being upheaved or even much disturbed by it. Even without being entirely clear about just what it is, we are all learning to take it for granted. It is a curious, peaceful sort of revolution, in which there is no general apprehension that old views are being outraged and ...
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2012
The source of genetic information in a plant cell is contained in nucleus, plastids, and mitochondria. Organelle transformation is getting a lot of attention nowadays because of its superior performance over the conventional and most commonly used nuclear transformation for obtaining transgenic lines.
Anjanabha, Bhattacharya +3 more
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The source of genetic information in a plant cell is contained in nucleus, plastids, and mitochondria. Organelle transformation is getting a lot of attention nowadays because of its superior performance over the conventional and most commonly used nuclear transformation for obtaining transgenic lines.
Anjanabha, Bhattacharya +3 more
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Organelles under the spotlight
Nature Reviews Molecular Cell Biology, 2015Kapitein and colleagues have used an optically controlled system that couples organelles and motor proteins to study the dynamics and roles of organelle transport.
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2011
Proteomics has significantly contributed to improve our understanding of cell structures and functions in the last decade. The possibility to identify large sets of proteins from minute amount of material, linked with the isolation of cellular organelles using various cell fractionation methods, has provided unique insights into the molecular ...
Sophie, Duclos, Michel, Desjardins
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Proteomics has significantly contributed to improve our understanding of cell structures and functions in the last decade. The possibility to identify large sets of proteins from minute amount of material, linked with the isolation of cellular organelles using various cell fractionation methods, has provided unique insights into the molecular ...
Sophie, Duclos, Michel, Desjardins
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Mitochondria-the suicide organelles
BioEssays, 2001One of the near-to-invariant hallmarks of early apoptosis (programmed cell death) is mitochondrial membrane permeabilization (MMP). It appears that mitochondria fulfill a dual role during the apoptotic process. On the one hand, they integrate multiple different pro-apoptotic signal transducing cascades into a common pathway initiated by MMP.
Guido Kroemer +2 more
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2009
The proteome of the cell is at the frontier of being too complex for proteomic analysis. Organelles provide a step up. Organelles compartmentalize the cell enabling a proteome, physiology and metabolism analysis in time and in space. Protein complexes separated by electrophoresis have been identified as the next natural level to characterize the ...
Matthias, Plöscher +4 more
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The proteome of the cell is at the frontier of being too complex for proteomic analysis. Organelles provide a step up. Organelles compartmentalize the cell enabling a proteome, physiology and metabolism analysis in time and in space. Protein complexes separated by electrophoresis have been identified as the next natural level to characterize the ...
Matthias, Plöscher +4 more
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The FASEB Journal, 2000
Lysosomes are membrane-bound cytoplasmic organelles involved in intracellular protein degradation. They contain an assortment of soluble acid-dependent hydrolases and a set of highly glycosylated integral membrane proteins. Most of the properties of lysosomes are shared with a group of cell type-specific compartments referred to as 'lysosome-related ...
Steve Caplan +3 more
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Lysosomes are membrane-bound cytoplasmic organelles involved in intracellular protein degradation. They contain an assortment of soluble acid-dependent hydrolases and a set of highly glycosylated integral membrane proteins. Most of the properties of lysosomes are shared with a group of cell type-specific compartments referred to as 'lysosome-related ...
Steve Caplan +3 more
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Emerging Topics in Life Sciences, 2019
One approach towards the creation of bottom-up synthetic biological systems of higher complexity relies on the subcompartmentalization of synthetic cell structures using artificially generated organelles — roughly mimicking the architecture of eukaryotic cells.
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One approach towards the creation of bottom-up synthetic biological systems of higher complexity relies on the subcompartmentalization of synthetic cell structures using artificially generated organelles — roughly mimicking the architecture of eukaryotic cells.
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Fractionation of Subcellular Organelles
Current Protocols in Cell Biology, 2015AbstractThis unit provides both a theoretical and a practical background to all the techniques associated with the application of differential and density gradient centrifugation for the analysis of subcellular membranes. The density gradient information focuses on the use of the modern gradient solute iodixanol, chosen for its ease of use, versatility,
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