Results 21 to 30 of about 1,088,075 (297)

The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals

open access: yesFrontiers in Molecular Biosciences, 2023
Vacuolar H+-ATPases (V-ATPases) acidify several organelles in all eukaryotic cells and export protons across the plasma membrane in a subset of cell types.
Farzana Tuli, Patricia M. Kane
doaj   +1 more source

Imaging of Endoplasmic Reticulum Ca2+ in the Intact Pituitary Gland of Transgenic Mice Expressing a Low Affinity Ca2+ Indicator

open access: yesFrontiers in Endocrinology, 2021
The adenohypophysis contains five secretory cell types (somatotrophs, lactotrophs, thyrotrophs, corticotrophs, and gonadotrophs), each secreting a different hormone, and controlled by different hypothalamic releasing hormones (HRHs).
Jonathan Rojo-Ruiz   +4 more
doaj   +1 more source

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

open access: yesNature Communications, 2016
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts ...
Yijian Rao   +4 more
doaj   +1 more source

A strategy to characterize chlorophyll protein interaction in LIL3

open access: yesPlant Methods, 2019
Background The function of proteins is at large determined by cofactors selectively bound to protein structure. Without chlorophyll specifically bound to protein, light harvesting and photosynthesis would not be possible.
Astrid Elisabeth Mork-Jansson   +1 more
doaj   +1 more source

Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome–Mitochondrion Interaction

open access: yesFrontiers in Pharmacology, 2022
Background: The interaction between lysosomes and mitochondria includes not only mitophagy but also mitochondrion–lysosome contact (MLC) that enables the two organelles to exchange materials and information.
Han Wang   +12 more
doaj   +1 more source

Bioanalysis of Eukaryotic Organelles [PDF]

open access: yesChemical Reviews, 2013
The function of biological cells is intimately associated with their internal organization, in which multiple subcellular structures have specialized roles. Such subcellular structures hold the secrets to normal cellular function, progression of disease, and the universe of interactions among biomolecules that define life.
Chad P, Satori   +6 more
openaire   +4 more sources

Organellar Evolution: A Path from Benefit to Dependence

open access: yesMicroorganisms, 2022
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
doaj   +1 more source

Organelle Zones

open access: yesCell Structure and Function, 2019
In research on cell biology, organelles have been a major unit of such analyses. Researchers have assumed that the inside of an organelle is almost uniform in regards to its function, even though each organelle has multiple functions. However, we are now facing conundrums that cannot be resolved so long as we regard organelles as functionally uniform ...
Kanae Sasaki, Hiderou Yoshida
openaire   +6 more sources

Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles

open access: yesFrontiers in Neuroscience, 2020
Alpha-synuclein (α-syn) is localized in cellular organelles of most neurons, but many of its physiological functions are only partially understood. α-syn accumulation is associated with Parkinson’s disease, dementia with Lewy bodies, and multiple system ...
Luis D. Bernal-Conde   +13 more
doaj   +1 more source

Interacting organelles [PDF]

open access: yesCurrent Opinion in Cell Biology, 2018
Eukaryotic cells are organized into membrane-bound organelles. These organelles communicate with one another through vesicular trafficking pathways and membrane contact sites (MCSs). MCSs are sites of close apposition between two or more organelles that play diverse roles in the exchange of metabolites, lipids and proteins.
Sarah Cohen   +2 more
openaire   +2 more sources

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