Results 21 to 30 of about 463,135 (398)

Chaperones and Proteostasis: Role in Parkinson’s Disease

open access: yesDiseases, 2020
Proper folding to attain a defined three-dimensional structure is a prerequisite for the functionality of a protein. Improper folding that eventually leads to formation of protein aggregates is a hallmark of several neurodegenerative disorders.
Neha Joshi   +2 more
doaj   +1 more source

Mitochondrial and chloroplast stress responses are modulated in distinct touch and chemical inhibition phases [PDF]

open access: yes, 2016
Previous studies have identified a range of transcription factors that modulate retrograde regulation of mitochondrial and chloroplast functions in Arabidopsis (Arabidopsis thaliana).
De Clercq, Inge   +6 more
core   +2 more sources

NOVOPlasty: de novo assembly of organelle genomes from whole genome data

open access: yesNucleic Acids Research, 2016
The evolution in next-generation sequencing (NGS) technology has led to the development of many different assembly algorithms, but few of them focus on assembling the organelle genomes.
Nicolas Dierckxsens   +2 more
semanticscholar   +1 more source

Fusing the 3’UTR of seed storage protein genes leads to massive recombinant protein accumulation in seeds

open access: yesScientific Reports, 2023
The demand for recombinant proteins is rising dramatically, and effective production systems are currently being developed. The production of recombinant proteins in plants is a promising approach due to its low cost and low risk of contamination of the ...
Masatake Kanai   +5 more
doaj   +1 more source

Mitochondrial quality control: from molecule to organelle

open access: yesCellular and Molecular Life Sciences, 2021
Mitochondria are organelles central to myriad cellular processes. To maintain mitochondrial health, various processes co-operate at both the molecular and organelle level. At the molecular level, mitochondria can sense imbalances in their homeostasis and
Alba Roca-Portoles, S. Tait
semanticscholar   +1 more source

Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]

open access: yes, 2018
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin   +3 more
core   +1 more source

GeSeq – versatile and accurate annotation of organelle genomes

open access: yesNucleic Acids Res., 2017
We have developed the web application GeSeq (https://chlorobox.mpimp-golm.mpg.de/geseq.html) for the rapid and accurate annotation of organellar genome sequences, in particular chloroplast genomes.
Michael Tillich   +6 more
semanticscholar   +1 more source

ER proteins decipher the tubulin code to regulate organelle distribution

open access: yesNature, 2021
Organelles move along differentially modified microtubules to establish and maintain their proper distributions and functions 1 , 2 . However, how cells interpret these post-translational microtubule modification codes to selectively regulate organelle ...
P. Zheng   +7 more
semanticscholar   +1 more source

Kinesin Light Chains Are Essential for Axonal Transport in Drosophila [PDF]

open access: yes, 1998
Kinesin is a heterotetramer composed of two 115-kD heavy chains and two 58-kD light chains. The microtubule motor activity of kinesin is performed by the heavy chains, but the functions of the light chains are poorly understood.
Beushausen, Sven   +4 more
core   +2 more sources

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

open access: yesNature Communications, 2016
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts ...
Yijian Rao   +4 more
doaj   +1 more source

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