Results 21 to 30 of about 1,088,075 (297)
Vacuolar H+-ATPases (V-ATPases) acidify several organelles in all eukaryotic cells and export protons across the plasma membrane in a subset of cell types.
Farzana Tuli, Patricia M. Kane
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The adenohypophysis contains five secretory cell types (somatotrophs, lactotrophs, thyrotrophs, corticotrophs, and gonadotrophs), each secreting a different hormone, and controlled by different hypothalamic releasing hormones (HRHs).
Jonathan Rojo-Ruiz +4 more
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The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts ...
Yijian Rao +4 more
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A strategy to characterize chlorophyll protein interaction in LIL3
Background The function of proteins is at large determined by cofactors selectively bound to protein structure. Without chlorophyll specifically bound to protein, light harvesting and photosynthesis would not be possible.
Astrid Elisabeth Mork-Jansson +1 more
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Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome–Mitochondrion Interaction
Background: The interaction between lysosomes and mitochondria includes not only mitophagy but also mitochondrion–lysosome contact (MLC) that enables the two organelles to exchange materials and information.
Han Wang +12 more
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Bioanalysis of Eukaryotic Organelles [PDF]
The function of biological cells is intimately associated with their internal organization, in which multiple subcellular structures have specialized roles. Such subcellular structures hold the secrets to normal cellular function, progression of disease, and the universe of interactions among biomolecules that define life.
Chad P, Satori +6 more
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Organellar Evolution: A Path from Benefit to Dependence
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
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In research on cell biology, organelles have been a major unit of such analyses. Researchers have assumed that the inside of an organelle is almost uniform in regards to its function, even though each organelle has multiple functions. However, we are now facing conundrums that cannot be resolved so long as we regard organelles as functionally uniform ...
Kanae Sasaki, Hiderou Yoshida
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Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles
Alpha-synuclein (α-syn) is localized in cellular organelles of most neurons, but many of its physiological functions are only partially understood. α-syn accumulation is associated with Parkinson’s disease, dementia with Lewy bodies, and multiple system ...
Luis D. Bernal-Conde +13 more
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Eukaryotic cells are organized into membrane-bound organelles. These organelles communicate with one another through vesicular trafficking pathways and membrane contact sites (MCSs). MCSs are sites of close apposition between two or more organelles that play diverse roles in the exchange of metabolites, lipids and proteins.
Sarah Cohen +2 more
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