Results 301 to 310 of about 463,135 (398)

Identification of presenilin mutations that have sufficient gamma-secretase proteolytic activity to mediate Notch signaling but disrupt organelle and neuronal health. [PDF]

Neurobiol Dis
Ashkavand Z, Ryan KC, Laboy JT, Patel R, Geller B, Norman KR.   +5 more
europepmc   +1 more source

Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury

Advanced Science, EarlyView.
ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang, Li Wang, Jian Sun, Yan Chen, Waseem Ali, Yonggang Ma, Ruilong Song, Xishuai Tong, Jiaqiao Zhu, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zou   +13 more
wiley   +1 more source

Impact of Drp1 Loss on Organelle Interaction, Metabolism, and Inflammation in Mouse Liver. [PDF]

Cells
Wang L, Nomura S, Hasuzawa N, Yokota S, Nagayama A, Ashida K, Rikitake J, Moriyama Y, Nomura M, Yamamoto K.   +9 more
europepmc   +1 more source

<b>A STUDY OF UNUSUAL INTRACELLULAR ORGANELLES AND ULTRASTRUCTURAL ORGANISATION OF THE EYE OF </b><i><b>GAMMARUS OCEANICUS</b></i><b> (SEGERSTRALE 1947) FIXED IN THE MIDNIGHT SUN OF THE SPITSBERGEN (SVALBARD) </b><b>SUMMER </b>

, 1985
Victor Benno Meyer‐Rochow
openalex   +2 more sources

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

Advanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang, Jiong Chen, Zhenhua Zhu, Hong Hu, Qinghui Zhang, Rongrong Jia, Na Wang, Shihao Xiang, Yong Zhou, Yuehong Wang, Ling Xu   +10 more
wiley   +1 more source

A high-resolution bovine mitochondrial co-expression network

Biology Open
Pâmela A. Alexandre, Kate Keogh, Antonio Reverter, Nicholas J. Hudson   +3 more
doaj   +1 more source

Mitochondrial‑endoplasmic reticulum crosstalk: Molecular mechanisms and implications for cardiovascular disease (Review). [PDF]

Mol Med Rep
Liu Y, Gong X, Xing S.
europepmc   +1 more source

A Nanomodulator Enhances Radiotherapy‐Induced In Situ Cancer Vaccine by Promoting Antigen‐Presenting of Tumor‐Associated Macrophage

Advanced Science, EarlyView.
A nanomodulator (Ft‐E64/Hf@Lipo) is developed, combining radiosensitizer hafnium (Hf) and the cysteine protease inhibitor E64, which cooperatively reinvigorated the antigen presentation of TAMs. Ft‐E64/Hf@Lipo sensitized‐RT generated abundant tumor neoantigens, and then E64/antigens, along with the apoptotic tumor cells, trafficked to TAMs via ...
Xiu Zhao, Mengli Li, Jun Li, Yueying Han, Yu Gong, Zhenzhong Zhang, Jinjin Shi, Cheng‐Yun Jin, Junjie Liu, Pilei Si   +9 more
wiley   +1 more source

Distribution of anionic sites on intracellular organelles: A study by labeling frozen thin-section with cationized ferritin.

, 1985
Kazushi Fujimoto, KAZU SHIGE OGAWA, Setsuko Kondo, Kazuo Ogawa   +3 more
openalex   +2 more sources

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Advanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan, Chun‐Miao Deng, Lin Tang, Shu‐Jun Li, Tao‐Yang Xu, Xian Wei, Xin‐Yi Zhang, Can‐Can Zheng, Li Deng, Cui Shao, Zhong‐Min Ouyang, Alfred King‐Yin Lam, Rong Zhang, Jun Liu, Xing‐Yuan Shi, Zhen‐Yu Pan, Wei Dai, Ming‐Liang He, Simon Law, Xu Li, Xiao‐Bing Chen, Cheng Zhou, Bin Li, Wen‐Wen Xu   +23 more
wiley   +1 more source