Results 31 to 40 of about 110,893 (161)
Regulation of Organelle Biogenesis [PDF]
We are grateful to the members of the Walter laboratory and of the many other laboratories whose work is reviewed for their helpful discussions, for their critical reading of this manuscript, and for making preprints available prior to publication. Because of space limitations, we were not able to include many of the primary references, and the readers
Jodi Nunnari, Peter Walter
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Cilia - the prodigal organelle [PDF]
Cilia are the oldest known cellular organelle, first described in 1675 by Anthony van Leeuwenhoek in protozoa [1]. He described them as 'incredibly thin feet, or little legs, which were moved very nimbly'. The term 'cilium' (Latin for eyelash) was probably first coined by Otto Muller in 1786 [2].
Peter K. Jackson, PL Beales
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Peroxisomes: Organelles at the crossroads [PDF]
Recent years have seen remarkable progress in our understanding of the function of peroxisomes in higher and lower eukaryotes. Combined genetic and biochemical approaches have led to the identification of many genes required for the biogenesis of this organelle.
Erdmann, R+3 more
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Endocytic organelles in three eukaryotic kingdoms evolved in parallel, according to Joel Dacks, Mark Field (University of Cambridge, UK), and Pak Poon (Dalhousie University, Halifax, Canada). Unlike mitochondria and chloroplasts, the membrane trafficking system did not arise through endosymbiosis; it evolved from within.
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In the early 1980s, cell biologists kept slamming into the same obstacle when they tried deploying antibodies to elucidate the working of the Golgi complex. True, use of antibodies to identify proteins (Bader et al., 1982; de Camilli et al., 1983a,b; Huttner et al., 1983; Weiss et al., 1984; Woodcock-Mitchell et al., 1982; Yen and Fields, 1981 ...
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Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics.
Mitochondria host vital cellular functions, including oxidative phosphorylation and co-factor biosynthesis, which are reflected in their proteome. At the cellular level plant mitochondria are organized into hundreds of discrete functional entities, which
Philippe Fuchs+16 more
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Assembly of the algal CO2-fixing organelle, the pyrenoid, is guided by a Rubisco-binding motif
A protein motif mediates targeting of proteins to the pyrenoid and appears to link the pyrenoid’s three subcompartments. Approximately one-third of the Earth’s photosynthetic CO2 assimilation occurs in a pyrenoid, an organelle containing the CO2-fixing ...
Moritz T. Meyer+9 more
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Acute Pancreatitis: A Multifaceted Set of Organelle and Cellular Interactions.
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with tissue injury and necrosis. The disease can be mild, involving only the pancreas, and resolve spontaneously within days or severe, with systemic inflammatory response
Aida Habtezion, A. Gukovskaya, S. Pandol
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ER membranes exhibit phase behavior at sites of organelle contact
Significance Membrane phase behavior in cells permits transient concentration of specific proteins and lipids into dynamic nanoscopic domains. Here, we tested the existence and role of such phase behavior in endoplasmic reticulum (ER) membranes ...
C. King+3 more
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Inter-organelle membrane contact sites: implications for lipid metabolism
This article supplements a recent Perspective by Scorrano et al. in Nature Communications [10 [ (1)]:1287] in which the properties and functions of inter-organelle membrane contact sites were summarized.
J. Vance
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