Results 71 to 80 of about 1,118,522 (291)

Bioavailability of Metal Ions and Evolutionary Adaptation

Life, 2012
The evolution of life on earth has been a long process that began nearly 3,5 x 109 years ago. In their initial moments, evolution was mainly influenced by anaerobic environments; with the rise of O2 and the corresponding change in bioavailability of ...
Rolando P. Hong Enriquez, Trang N. Do
doaj   +1 more source

Charge‐Induced Morphing Gels for Bioinspired Actuation

Advanced Functional Materials, EarlyView.
This study introduces a novel electroactive actuation mechanism that enables the gel material to generate substantial and reversible shape‐changing while preserving topological and isochoric (volumetric) equivalence. The resultant morphing behaviors can mimic the movements of muscle‐driven organelles in nature, including cilia‐like beating and ...
Ciqun Xu, Saba Firouznia, Charl F. J. Faul, Majid Taghavi, Jonathan Rossiter   +4 more
wiley   +1 more source

Multi-color fluorescence live-cell imaging in Dictyostelium discoideum

Cell Structure and Function
The cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been extensively studied in cell and developmental biology. D. discoideum is unique in that they are genetically tractable, with a wealth of data accumulated over half a ...
Hidenori Hashimura, Satoshi Kuwana, Hibiki Nakagawa, Kenichi Abe, Tomoko Adachi, Toyoko Sugita, Shoko Fujishiro, Gen Honda, Satoshi Sawai   +8 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

MitoLandscape, a semi-automated pipeline for subcellular localization and quantification of mitochondria

Frontiers in Cell and Developmental Biology
The precise characterization of mitochondrial morphology and subcellular localization provides crucial insights into cellular metabolic states and developmental fates.
Enrico Negri, Virginia Fernández, Víctor Borrell   +2 more
doaj   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

The walking dead: sequential nuclear and organelle destruction during hair development [PDF]

, 2018
L.A. Jones, D.P. Harland, B.B. Jarrold, J.E. Connolly, M.G. Davis   +4 more
openalex   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Research advances on Golgi stress response in bone metabolism

Kouqiang hemian waike zazhi
During the growth, development, and injury repair processes of mammals, organelles undergo self-regulation through a series of complex regulatory mechanisms when subjected to interference from inside or outside, in order to maintain cellular homeostasis.
NIU Pingping, SUN Yao
doaj   +1 more source

A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis [PDF]

, 2006
Alexander C. Theos, Steven T. Truschel, Danièle Tenza, Ilse Hurbain, Dawn C. Harper, Joanne F. Berson, Penelope C. Thomas, Graça Raposo, Michael S. Marks   +8 more
openalex   +1 more source