Results 81 to 90 of about 463,135 (398)
The Journal of Cell Biology, 2001 ![Graphic][1] Swimming is a problem despite remaining lipid rafts. Kurzchalia/AAAS By knocking out a single gene for caveolin-1, Teymuras Kurzchalia (Max Planck Institute, Dresden, Germany) and colleagues have ablated a special subset of lipid rafts called caveolae.
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Putting organelles in their place
eLife, 2021 Experiments in C. elegans reveal new insights into how the ANC-1 protein helps to anchor the nucleus and other organelles in place.
Ulm, Patricia, Jantsch, Verena
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From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
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Bridging molecular and cellular neuroscience with proximity labeling technologies
Experimental and Molecular MedicineProximity labeling (PL) techniques have advanced neuroscience by revealing the molecular interactions that govern neural circuits. From foundational tools such as BioID and APEX to recent innovations such as TurboID and light-activated systems, PL ...
Jun-Gyu Lee +2 more
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The early days of plastid retrograde signaling with respect to replication and transcription
Frontiers in Plant Science, 2013 The plastid signal was originally defined as a pathway that informs the nucleus of the chloroplast status and results in the modulation of expression of nuclear-encoded plastid protein genes.
Kan eTanaka, Mitsumasa eHanaoka
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Freeze/thaw stress induces organelle remodeling and membrane recycling in cryopreserved human mature oocytes [PDF]
, 2016 Purpose: Our aim was to evaluate the ultrastructure of human metaphase II oocytes subjected to slow freezing and fixed after thawing at different intervals during post-thaw rehydration.
Albani, E. +8 more
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Cilia - the prodigal organelle [PDF]
Cilia, 2012 Cilia are the oldest known cellular organelle, first described in 1675 by Anthony van Leeuwenhoek in protozoa [1]. He described them as 'incredibly thin feet, or little legs, which were moved very nimbly'. The term 'cilium' (Latin for eyelash) was probably first coined by Otto Muller in 1786 [2].
Peter K. Jackson, PL Beales
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Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
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Cell biological insights into human STING variants
Cell Structure and FunctionStimulator of interferon genes (STING) is an endoplasmic reticulum (ER)-localized transmembrane protein. STING induces type I interferon and inflammatory responses against a variety of double-stranded DNA (dsDNA) viruses, which is critical for limiting ...
Shogo Koide +5 more
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Drosophila mRNA Localization During Later Development: Past, Present, and Future
Frontiers in Genetics, 2019 Multiple mechanisms tightly regulate mRNAs during their transcription, translation, and degradation. Of these, the physical localization of mRNAs to specific cytoplasmic regions is relatively easy to detect; however, linking localization to functional ...
Sarah C. Hughes +2 more
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