Results 91 to 100 of about 1,049,966 (302)
مجله دانشکده پزشکی اصفهان, 2013 Organic acidurias (or organic acidemias) are a group of inherited metabolic disorders usually caused by loss or lack of the activity of one enzyme in the catabolic pathway of amino acids, fatty acids, carbohydrates, cholesterol, biogenic amines, nucleic ...
Morteza Pourfarzam, Bahara Barati
doaj
Microbiology Indonesia, 2014 Some organic acids derived from lignin degradation in peat soil have significant role in lowering pH of peat soil and have phytotoxic effect for plant.
DIANA NURANI, KOESNANDAR KOESNANDAR
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Concentrations of higher dicarboxylic acids C5 – C13 in fresh snow samples collected at the High Alpine Research Station Jungfraujoch during CLACE 5 and 6 [PDF]
, 2008 Samples of freshly fallen snow were collected at the high alpine research station Jungfraujoch (Switzerland) in February and March 2006 and 2007, during the Cloud and Aerosol Characterization Experiments (CLACE) 5 and 6. In this study a new technique has
Fries, Elke +5 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Amino acids in a Fischer Tropsch type synthesis [PDF]
One postulation is described for the presence of organic compounds in meteorites which states that they were formed during the condensation of the solar nebula.
Brown, D. L., Lawless, J. G.
core +1 more source
Influence of ligand shape and steric hindrance on the composition of the nanocrystal ligand shell [PDF]
, 2015 Organic ligands play a key role in the synthesis of colloidal semiconductor nanocrystals or quantum dots. Generally they consist of a functional group and an aliphatic chain, with carboxylic acids, thiols and phosphonic acids as typical examples.
De Nolf, Kim +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Towards a new method for coating heritage lead [PDF]
, 2014 Ethanolic solutions of long-chain carboxylic acids can be applied to lead metal substrates to form a coating of lead carboxylate which provides protection against atmospheric pollutants.
Adriaens, Mieke +5 more
core +2 more sources