Results 71 to 80 of about 1,994,751 (249)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Research Program for Organic Food and Farming in Finland [PDF]
, 2005 The Finnish Ministry of Agriculture and Forestry started a three-year Research Programme on Organic Food and Farming in 2003. The programme consists of 15 projects on different themes covering the whole food chain and has an annual budget of about 2.2 ...
Nykaenen, Arja, Nykänen, Arja
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
COMPREHENSIVE REVIEW OF ORGANIC ADDITIVES PROPERTIES AND THEIR EFFECTS ON CHARACTERISTICS OF PERFORMANCE AND EMISSIONS IN DIESEL ENGINES [PDF]
Scientific Journal of Silesian University of Technology. Series TransportRecently, organic additives have shown an essential role in improving fuel quality, promoting combustion efficiency, and minimizing pollutants. This research examines the properties and effects of several organic compounds on the performance and emission
Abdelrahman ALAA +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Relevance of mycotoxins to product quality and animal health in organic farming [PDF]
, 2002 Organic farming is not generally more endangered by the risk of contamination of the products with mycotoxins than other farming systems. Knowledge about the influence of litter beddings on mycotoxin exposure of livestock is rare.
Weißmann, Friedrich +1 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Australian Organic: Market Report 2018
, 2018 This is the sixth Australian Organic Market Report (AOMR), which aims to assist industry, governments, media, researchers, representative organisations and others to assess market status, identify potential growth areas, report on areas of significance ...
Lawson, Andrew +7 more
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source