Results 61 to 70 of about 1,586,299 (311)

Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]

open access: yes, 2014
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Amphiphilic Nanographene With Aggregation‐Induced Type‐I Photodynamic Properties

open access: yesAggregate
Fluorescent graphene quantum dots (GQDs) have emerged as promising phototheranostic agents. However, most of the reported GQDs only show Type‐II photodynamic (PD) effect, which is not effective in the hypoxic tumor interior. Moreover, little is known yet
Hao Zhao   +8 more
doaj   +1 more source

Distribution of Organic Carbon in the Sediments of Xinxue River and the Xinxue River Constructed Wetland, China. [PDF]

open access: yesPLoS ONE, 2015
Wetland ecosystems are represented as a significant reservoir of organic carbon and play an important role in mitigating the greenhouse effect. In order to compare the compositions and distribution of organic carbon in constructed and natural river ...
Qingqing Cao   +4 more
doaj   +1 more source

Reduced tillage and green manures for sustainable organic cropping systems [PDF]

open access: yes, 2011
The overall aim of the project Reduced tillage and green manures for sustainable organic cropping systems (TILMAN-)ORG are to design improved organic cropping systems with enhanced productivity and nutrient use efficiency, more efficient weed management ...
Helga , Willer, Paul, Mäder
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Carbon isotope anomaly in the major plant C-1 pool and its global biogeochemical implications [PDF]

open access: yes, 2004
We report that the most abundant C-1 units of terrestrial plants, the methoxyl groups of pectin and lignin, have a unique carbon isotope signature exceptionally depleted in C-13.
Hamilton, JTG   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The H/C Molar Ratio and Its Potential Pitfalls for Determining Biochar's Permanence

open access: yesGCB Bioenergy
Biochar carbon removal (BCR) is widely recognized as a globally feasible technique for removing CO2 from the atmosphere and storing carbon in a stable form within the environment.
Henrik I. Petersen, Hamed Sanei
doaj   +1 more source

Silicate weathering and carbon cycle controls on the Oligocene-Miocene transition glaciation [PDF]

open access: yes, 2017
Changes in both silicate weathering rates and organic carbon burial have been proposed as drivers of the transient “Mi-1” glaciation event at the Oligocene-Miocene transition (OMT; ~23 Ma).
Algeo   +107 more
core   +3 more sources

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