Results 81 to 90 of about 36,235 (291)

Time-resolved measurements of sugar-binding-induced conformational changes in the melibiose permease from Escherichia coli

, 2008
The melibiose permease (MelB) of E.coli functions as a secondary-active symporter by using the electrochemical H+, Na+, or Li+ gradient to accumulate, e.g., melibiose [review in Pourcher et al. 1990a].
Meyer-Lipp, Kerstin
core  

Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct [PDF]

, 2008
Considering that short, mainly heterochiral, polypeptides with a high glycine content are expected to have played a prominent role in evolution at the earliest stage of life before nucleic acids were available, we review recent knowledge about ...
Milner-White, E.J., Russell, M., Russell Michael J, Milner-White E James   +3 more
core   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Allele frequencies and genotype distribution of three metformin transporter polymorphisms in Mexican population and their application in pharmacogenomics of type 2 diabetes

Frontiers in Pharmacology
BackgroundMetformin is the first-line antidiabetic therapy for type 2 diabetes in Mexico, despite recent recommendations highlighting alternatives like GLP-1 receptor agonists for individuals with obesity.
Oscar I. Chávez-Arreola, Brissia Lazalde, Marisol López-López, Alberto Ortega-Vázquez, Alberto Ortega-Vázquez, Quitzia L. Torres-Salazar   +5 more
doaj   +1 more source

Structural basis of Na+-independent and cooperative transport in the L-carnitine/gamma-butyrobetaine antiporter CaiT

, 2011
Der L-Carnitin/gamma-Butyrobetain Antiporter CaiT ist ein Mitglied der Betain/Carnitin/Cholin Transporter (BCCT) Familie. Sekundärtransporter der BCCT Familie transportieren Substrate, die eine positiv-geladene quartäre Ammoniumgruppe besitzen.
Schulze, Sabrina
core  

Recent advances in exploring physiology and biodiversity of ectomycorrhizas highlight the functioning of these symbioses in ecosystems [PDF]

, 2000
Ectomycorrhizas, the dominating mycorrhizal symbiosis in boreal, temperate and some tropical forests, are formed by 5000-6000 species of the asco- and basidiomycetes.
Nehls, Uwe, Munch, Jean Charles, Hampp, Rüdiger, Charcosset, Jean-Yves, Buscot, François, Gardes, Monique   +5 more
core   +1 more source

MPP+-induced changes in cellular impedance as a measure for organic cation transporter (SLC22A1-3) activity and inhibition

, 2022
The organic cation transporters OCT1-3 (SLC22A1-3) facilitate the transport of cationic endo- and xenobiotics and are important mediators of drug distribution and elimination.
Hubert Sijben, Tamara Mocking, Mocking, T.A.M., Yimé Vermeulen, Vermeulen, Y., Sijben, H.J., Laura Heitman, Adriaan IJzerman, IJzerman, A.P., Heitman, L.H.   +9 more
core   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tissues

Frontiers in Physiology
Epizootic shell disease (ESD) is characterized by shell erosion, pitting, and melanization in the American lobster (Homarus americanus) and is associated with a polymicrobial infection.
Minseo Kim, Dianjun Cao, Vincent Cavaleri, Kyudong Han, Kyudong Han, Kyudong Han, Seyoung Mun, Seyoung Mun, Seyoung Mun, Soo Jin Jeon   +9 more
doaj   +1 more source

An extended substrate spectrum of the proton organic cation antiporter and relation to other cation transporters

Most central nervous system (CNS) active drugs are organic cations, which need carrier proteins for efficient transfer through the blood–brain barrier (BBB).
Redeker, Kyra‐Elisa Maria, Ali Khan, Cauzar, Brockmöller, Jürgen, Kirsch, Nicolai   +3 more
core   +1 more source