Results 31 to 40 of about 47,513 (255)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Anticancer Activity of Phytochemicals from Nepalese Plants: A Review of Active Phytochemicals and Screening Methods

Natural Product Communications
Medicinal plants have long been sought after as a source of potentially valuable compounds to combat cancer. This review purposes that the phytochemicals found in Nepalese medicinal plants possess significant potential anticancer activity, which calls ...
Anup Luitel, Lalit Mohan Pant, Niru Thapa, Manika Shrestha, Anup Adhikari, Ronak Shrestha, Ashwinee Kumar Shrestha, Rajan Shrestha, Janardan Lamichhane   +8 more
doaj   +1 more source

Effect of FYM and silicon on productivity of organic sweet corn (Zea mays saccharata)

The Indian Journal of Agricultural Sciences, 2021
Sweet corn (Zea mays saccharata) under organic farming is becoming popular in India. Field experiment was conducted during 2019 and 2020 to investigate the effect of nitrogen through FYM and silicon on growth and yield of sweet corn under organic farming
B SRI SAI SIDDARTHA NAIK, S K SHARMA, ROSHAN CHOUDHARY, SHARVAN KUMAR YADAV, GAJANAND JAT, BHAWANI SINGH PRAJAPTH   +5 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Genome‐wide association study reveals the genetic architecture of drought tolerance in maize using yield‐based resistance indices and transcriptomic evidence

The Plant Genome
Drought is a major environmental factor limiting maize (Zea mays L.) production worldwide. Unraveling the genetic basis of drought tolerance and pinpointing key loci and candidate genes are fundamental to the molecular breeding of maize with enhanced ...
Haoyang Li, Xurong Hu, Pengyan Zhang, Yueying Zhao, Yinglu Song, Zheng Zhang, Huahu Bu, Jianzhong Chang   +7 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Effects of arbuscular mycorrhizal fungi on the bacterial communities of three compartments in strawberry roots

BMC Plant Biology
Background Arbuscular mycorrhizal (AM) fungi can regulate microbial communities in rhizosphere soil and promote plant growth. However, few studies have examined the regulated differences in microbial communities between new and old roots.
Jing Xu, Yuxue Duan, Wenjing Wu, Fengwei Diao   +3 more
doaj   +1 more source

A Comparative Study on the Effect of Biogas Residue Soil Conditioner on Dryland Maize

Agronomy
To investigate the adaptability and efficacy of biogas residue soil conditioner in conjunction with other commercially available soil conditioners in arid conditions, a study was conducted using dryland maize as the experimental crop.
Jing Zhou, Xiuhong Wang, Baoping Wang, Jitao Zhang, Xiaochen Zhang, Xiangyuan Shi   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Holobiont-based genetic analysis reveals new plant and microbial markers for resistance against a root rot pathogen complex in pea

BMC Plant Biology
Background The pea root rot complex is caused by various soil-borne pathogens that likely reinforce each other, influencing the composition of the root microbiome and leading to significant yield reductions.
Michael Schneider, Valentin Gfeller, Daniel Ariza-Suarez, Lukas Wille, Klaus H. Oldach, Natacha Bodenhausen, Martin Hartmann, Pierre Hohmann, Bruno Studer, Monika M. Messmer   +9 more
doaj   +1 more source