Results 81 to 90 of about 5,798,114 (363)

Palladium-catalyzed enantioselective β-hydride elimination for the construction of remote stereocenters

Nature Communications
The β-H elimination is a crucial elementary step in transition-metal catalysis, but controlling the stereochemistry of this process has been underdeveloped.
Shaozi Sun, Shengnan Sun, Weiwei Zi
doaj   +1 more source

Mechanical-robust and recyclable polyimide substrates coordinated with cyclic Ti-oxo cluster for flexible organic solar cells

npj Flexible Electronics, 2022
With the rapid development of flexible optoelectronic devices, recyclability is highly desirable for alleviating resource waste and environmental pollution, but remains challenging.
Guangcong Zhang, Qiaomei Chen, Chengcheng Xie, Yongmei Wang, Chaowei Zhao, Chengyi Xiao, Yen Wei, Weiwei Li   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Application of Comb-Type Fluorocarbon Polymer Surfactants as Dispersants in Insecticidal and Fungicidal Suspension Concentrates

Molecules
To investigate the application of novel comb-type fluorinated polymeric surfactants in suspension concentrates (SCs), we used the optimized surfactants (Comb-S 1, Comb-S 2, and Comb-S 3) as dispersants, with commercial dispersants as controls, to prepare
Jingjing Zhang, Lingyun Song, Ruiying Ma, Junjie Kou, Yuxiu Liu, Qingmin Wang   +5 more
doaj   +1 more source

The association between organic matter and clay minerals in carbonaceous chondrites [PDF]

, 2001
There is an established relationship between organic matter content and aqueous alteration processes [1,2]. However, the relationship between meteoritic organic matter and individual aqueously generated mineral matrix phases is poorly understood ...
Bland, P. A., Franchi, I. A., Gilmour, I., Pearson, V. K., Sephton, M. A.   +4 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Sensitivity of labile carbon fractions to tillage and organic matter management and their potential as comprehensive soil quality indicators across pedoclimatic conditions in Europe

Ecological Indicators, 2019
Soil quality is defined as the capacity of the soil to perform multiple functions, and can be assessed by measuring soil chemical, physical and biological parameters.
Giulia Bongiorno, E. Bünemann, Chidinma U. Oguejiofor, J. Meier, G. Gort, R. Comans, P. Mäder, L. Brussaard, Ron G.M. de Goede   +8 more
semanticscholar   +1 more source

Microbial carbon mineralization in tropical lowland and montane forest soils of Peru [PDF]

, 2016
Climate change is affecting the amount and complexity of plant inputs to tropical forest soils. This is likely to influence the carbon (C) balance of these ecosystems by altering decomposition processes e.g., "positive priming effects" that accelerate ...
Bardgett, Richard D., Ccahuana, Adan J. Q., McNamara, Niall P., Meir, Patrick, Nottingham, Andrew T., Ostle, Nicholas, Salinas, Norma, Stott, Andrew W., Whitaker, Jeanette   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source