Results 91 to 100 of about 1,559,720 (313)

Enantioselective synthesis of chiral amides by carbene insertion into amide N–H bond

open access: yesNature Communications
Chiral amides are important structure in many natural products and pharmaceuticals, yet their efficient synthesis from simple amide feedstock remains challenge due to its weak Lewis basicity.
Xuan-Ge Zhang   +4 more
doaj   +1 more source

Environmental impact of organic agriculture in temperate regions [PDF]

open access: yes, 2012
Can organic agriculture elaborate a scientifically based, resource-efficien and agroecological approach to low-input farm management? This review examines the literature from temperate regions, with a particular emphasison Canadian and USstudies that ...
Bhatta, G.D., Halberg, N., Lynch, D.H.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Organic and conservation agriculture, the best of both worlds? [PDF]

open access: yes
In millions of years huge amounts of organic matter were stored in the soil as organic matter or fossil energy carriers as oil, gas and coal. We make use of these stocks to supply us with energy and to be able to grow plants for our needs.
Sukkel, W.
core   +1 more source

Organic Fruit Production in Europe [PDF]

open access: yes, 2002
PART I: SHORT HISTORY OF ORGANIC FARMING The organic fruit production in Europe is not only a matter of statistics, regulations and tables but also has a meaningful historical background.
Weibel, Franco
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Iron-catalyzed alkyne alkylzincation affected by counterions

open access: yesNature Communications
Metal complex catalysts typically comprise three components: ligands, central metals, and counterions. The counterion profoundly influences the activity and selectivity of numerous catalytic reactions, while such a phenomenon is rarely observed in ...
Lu-Jie Li   +4 more
doaj   +1 more source

Structures and growth pathways of AunCln+3- (n ≤ 7) cluster anions

open access: yesFrontiers in Chemistry
Gold chloride clusters play an important role in catalysis and materials chemistry. Due to the diversity of their species and isomers, there is still a dearth of structural studies at the molecular level.
Shiyin Xu   +8 more
doaj   +1 more source

Incorporation of nitrogen from crop residues into light fraction organic matter in soils with contrasting management histories [PDF]

open access: yes, 2008
The proportion of N from crop residues entering the light-fraction organic matter (LFOM) pool was investigated in soils with contrasting soil organic matter and microbial characteristics arising from different management histories.
Bending, G. D., Turner, Mary K.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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