Results 81 to 90 of about 1,559,720 (313)

Simulating Soil Organic Matter Transformations with the New Implementation of the Daisy Model [PDF]

, 2001
Daisy is a well-tested deterministic, dynamic soil-plant-atmosphere model, capable of simulating water balance, nitrogen balance and losses, development in soil organic matter and crop growth and production in crop rotations under alternate management ...
Bruun, Sander, Hansen, Dr. Søren, Jensen, Dr. Lars Stoumann, Petersen, Anders   +3 more
core  

Tracking nitrogen losses in a greenhouse crop rotation experiment in North China using the EU-Rotate_N simulation model [PDF]

, 2010
Vegetable production in China is associated with high inputs of nitrogen, posing a risk of losses to the environment. Organic matter mineralisation is a considerable source of nitrogen (N) which is hard to quantify.
Ad-hoc-Arbeitsgruppe Boden, Addiscott, Cabrera, Chen, Chunguang Jiang, Claas Nendel, Clive Rahn, Fox, Fox, Gollany, Greenwood, Guo, Guo, He, He, He, Houba, Ju, Ju, Kotsiras, Li, Nash, Nendel, Nendel, Qing Chen, Rahn, Ramos, Ruiying Guo, Shen, Willmott, Zhang, Zhou, Zhu   +32 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Biomimetic Dehydrogenative Intermolecular Formal Allylic Amidation of Branched α‐Olefins

Advanced Science
Allylic amide moieties are commonly encountered in natural products and are privileged structures in pharmaceuticals and agrochemicals. Moreover, because allylic amide can be to converted into an array of high‐value motifs, they have been widely employed
Xiaoyang Fu, Jiarui Tian, Mingjun Zhang, Yue Jing, Yuxiu Liu, Hongjian Song, Qingmin Wang   +6 more
doaj   +1 more source

Scanning micro-raman spectroscopy on carbon-rich residues of primitive chondrites: A tool for chondrite classification and stardust analysis [PDF]

, 2005
We present results obtained by Raman spectroscopy of various organic residues of primitive chondrites in order to better characterize the microstructural state of the organic matter. These results will be correlated with the petographic classification of
Alexander, C. M. O'D., Busemann, H., Fries, M., Nittler, L., Steele, A.   +4 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Thermochromism of Model Organic Aerosol Matter [PDF]

, 2010
Laboratory experiments show that the optical absorptivity of model organic matter is not an intrinsic property, but a strong function of relative humidity, temperature, and insolation.
Colussi, A. J., Guzmán, Marcelo I., Hoffmann, M. R., Rincón, Angela G.   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source