Results 51 to 60 of about 4,128,607 (290)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Enrichment factors for organic matter in the SML in Daya Bay.

open access: yes, 2018
Enrichment factors for organic matter in the SML in Daya Bay.
Wei-Hong He (5014208)   +5 more
core   +1 more source

Sediment community responses to marine vs. terrigenous organic matter in a submarine canyon [PDF]

open access: yes, 2013
The Whittard Canyon is a branching submarine canyon on the Celtic continental margin, which may act as a conduit for sediment and organic matter (OM) transport from the European continental slope to the abyssal sea floor. In situ stable-isotope labelling
Huvenne, V.A.I.   +9 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nitrate elimination by denitrification in hardwood forest soils of the Upper Rhine floodplain – correlation with redox potential and organic matter [PDF]

open access: yes, 2002
Denitrification in floodplains is a major issue for river- and groundwater quality. In the Upper Rhine valley, floodplain forests are about to be restored to serve as flood retention areas (polders).
Trémolières, Michèle   +2 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

High-frequency sequence stratigraphy and organic matter enrichment patterns of the Carboniferous Karawuyi Formation, Southwestern Tarim Basin

open access: yesFrontiers in Earth Science
The Carboniferous strata in the southwestern Tarim Basin constitute one of the major source-rock intervals in the Tarim Basin and have considerable hydrocarbon-generating potential.
Hao Li   +8 more
doaj   +1 more source

Ecological networks of dissolved organic matter and microorganisms under global change

open access: yesNature Communications, 2022
Microbes are intimately linked with the fate of organic matter. Here the authors develop an ecological network framework and show how microbes and dissolved organic matter interact along global change drivers of temperature and nutrient enrichment via ...
Ang Hu   +11 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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