Results 71 to 80 of about 4,128,607 (290)

Effects of dissolved organic matter and nitrification on biodegradation of pharmaceuticals in aerobic enrichment cultures

open access: yesScience of The Total Environment, 2018
Natural dissolved organic matter (DOM) and nitrification can play an important role in biodegradation of pharmaceutically active compounds (PhACs) in aerobic zones of constructed wetlands (CWs). This study used an enrichment culture originating from CW sediment to study the effect of DOM and nitrification on aerobic biodegradation of seven PhACs.
He, Yujie   +4 more
openaire   +3 more sources

Differential enrichment mechanisms and quantitative evaluation on controlling factors of organic matter in Cambrian Qiongzhusi Formation shale in Deyang-Anyue rift trough, Sichuan Basin, China

open access: yesPetroleum Exploration and Development
Based on microscopic observations, total organic carbon (TOC) content measurements, and major, trace, and rare earth element analyses of core samples from the Cambrian Qiongzhusi Formation shale at different structural positions within the Deyang–Anyue ...
Caihua Lin   +10 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Paleoenvironmental characteristics of continental shale and its significance to organic matter enrichment: Taking the fifth member of Xujiahe Formation in Tianfu area of Sichuan Basin as an example

open access: yesOpen Geosciences
Lake-phase organic-rich shales are widely developed in the fifth member (Xu5 Member) of the Triassic Xujiahe Formation in the Sichuan Basin. However, due to the lack of understanding of the paleoclimate and paleoenvironment, the mechanism of organic ...
Yang Jian   +8 more
doaj   +1 more source

The Impact of Lamina Characteristics and Types on Organic Matter Enrichment of Chang 73 Submember in Ordos Basin, NW China

open access: yesGeofluids, 2022
The Chang 7 member in Ordos Basin is an important shale oil exploration layer, with new shale-oil discoveries in recent years. The Chang 73 submember is rich in organic shale, which is the main source rock of shale oil in the Yanchang Formation. In order
Congsheng Bian   +8 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Organic matter enrichment model of fine-grained rocks in volcanic rift lacustrine basin: A case study of lower submember of second member of Lower Cretaceous Shahezi Formation in Lishu rift depression of Songliao Basin, NE China

open access: yesPetroleum Exploration and Development
Based on sedimentary characteristics of the fine-grained rocks of the lower submember of second member of the Lower Cretaceous Shahezi Formation (K1sh2L) in the Lishu rift depression, combined with methods of organic petrology, analysis of major and ...
Huanyu XIE   +3 more
doaj   +1 more source

Development of Upwelling during the Sedimentary Period of the Organic-Rich Shales in the Wufeng and Longmaxi Formations of the Upper Yangtze Region and Its Impact on Organic Matter Enrichment

open access: yesJournal of Marine Science and Engineering, 2019
This study uses logging data, mineral component content, total organic carbon (TOC) content, and microscopic characteristics of the organic-rich shales in the Wufeng and Longmaxi Formations, as well as data reported by other researchers, to demonstrate ...
Shao-Ze Zhao   +8 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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