Results 71 to 80 of about 2,087,694 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ashes for organic farming [PDF]
, 2013 Nowadays only eight percent of the cultivated field area is used for organic farming. The Ministry of Agriculture and Forestry has published the guidelines for the program of organic farming to diversify the supply and the consumption of organic food ...
Heinonen, M. +3 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Social-ecological dynamics of aggregate mining in Ouagadougou, Burkina Faso
Scientific ReportsWhile traditional materials like clay-based adobe bricks are common in Burkina Faso, rapid urbanization in its capital, Ouagadougou, has driven a shift to more durable construction materials.
Katharina Salomea Hemmler +3 more
doaj +1 more source
Egyptian Journal of Biological Pest Control, 2018 The present study was carried out in greenhouses, on sweet pepper crops, during the winter plantations 2015–2016 and 2016–2017 in a commercial farm located at Berkash district, Giza, Egypt.
S. A. El Arnaouty +3 more
doaj +1 more source
Why regionality is an important value in organic agriculture: the case of the Netherlands [PDF]
, 2006 Organic agriculture is a system of production and consumption in which values play a prominent role. The new IFOAM principles reflect the current worldwide consensus on the most important values of organic agriculture.
de Wit, Jan, Prins, Udo, Verhoog, Henk
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Optimising production systems for organic pig production (OF0169) [PDF]
, 2002 This is the final report of Defra project OF0169. There is a more comprehensive Executive Summary at the start of the attached main report. The overall objective of this project was to generate the scientific and financial information necessary to ...
Day, Dr Jon, Martins, Ms Anne
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source