Results 61 to 70 of about 602,894 (266)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Effect of Parity on the Quality of Colostrum of Holstein Dairy Cows in the Organic Production System. [PDF]

open access: yesAnimals (Basel), 2023
Grodkowska K   +7 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Time series analysis of CORONA and Landsat data reveals agro-pastoral landscape dynamics in Nurota, Uzbekistan (1968–2023)

open access: yesEnvironmental Challenges
Little is known about land use and land cover (LULC) changes in the semi-arid agro-pastoral landscapes of Nurota, Uzbekistan (1968–2023). Using object-based and SVM classification methods, we mapped seven main LULC classes using a combination of CORONA ...
Khaytbay Artikov   +4 more
doaj   +1 more source

Orius albidipennis (Rueter) as an effective biocontrol agent against Tetranychus urticae Koch on pepper crops in greenhouse in Egypt

open access: yesEgyptian Journal of Biological Pest Control, 2018
The present study was carried out in greenhouses, on sweet pepper crops, during the winter plantations 2015–2016 and 2016–2017 in a commercial farm located at Berkash district, Giza, Egypt.
S. A. El Arnaouty   +3 more
doaj   +1 more source

The Influence of Cold-Pressed Linseed Cake Supplementation on Fatty-Acid Profile and Fat-Soluble Vitamins of Cows' Milk in an Organic Production System. [PDF]

open access: yesAnimals (Basel), 2023
Puppel K   +9 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Towards large-scale analyses of settlement patterns in urbanizing landscapes—findings of first studies for India, Egypt, and China

open access: yesScientific Reports
Improved ability to assess and categorize the spatial characteristics of settlement patterns is required for a deeper understanding of how urbanization is driving land use and land cover transformation and its effects.
Thanh Thi Nguyen   +6 more
doaj   +1 more source

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