Results 101 to 110 of about 557,484 (296)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Functionalized boron nitride membranes with ultrafast solvent transport performance for molecular separation

open access: yesNature Communications, 2018
2D materials show promise for membrane filtration technologies, but their permeance to organic solvents is typically poor. Here, the authors prepare functionalized boron nitride membranes with high flux and high molecular separation performances in both ...
Cheng Chen   +6 more
doaj   +1 more source

Hydrogen bond based noncovalent association in the semi-fluorous solvent perfluorobutyl-methyl ether: Host-host and host-guest association of the host 1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-decyl)-3-pyridin-2-yl-urea [PDF]

open access: yes, 2013
A fluorous pyridyl-urea, 1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-3-pyridin-2-yl-urea, was prepared to act as a host and analyzed by 1H NMR inCD2Cl2 and perfluorobutyl-methyl ether (HFE7100).
McGowan, Candace
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Stress corrosion cracking of titanium alloys: SCC velocity: concentration of TiCl3 [PDF]

open access: yes
Stress corrosion cracking of titanium alloys, velocity of cracking in aqueous and methanol solutions and halogenated organic solvents, concentration of TiCl3 in ...
Beck, T. R., Blackburn, M. J.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effects of Occupational Exposure with Mixture of Aromatic Organic Solvents on Liver Enzymes in Workers of an Automobile Plant

open access: yesArmaghane Danesh Bimonthly Journal, 2009
Introduction & Objective: Organic solvents have a broad range of application in industry. Hepatotoxicity of different organic halogenated solvents like carbon tetrachloride has been verified in numerous studies however, studies investigating the ...
MS Attarchi   +3 more
doaj  

Cytotoxic Effects of Some Common Organic Solvents on MCF-7, RAW-264.7 and Human Umbilical Vein Endothelial Cells

open access: yesAvicenna Journal of Medical Biochemistry, 2016
Background Organic solvents are widely used in cell biology experiments. Despite increasing the solubility, they have some moderate toxic effects. Therefore, selecting the appropriate solvent along with the use of suitable concentration insures
Jamalzadeh   +6 more
doaj   +1 more source

The wheat straw lignin as renewable polyol for polyurethanes elastomers [PDF]

open access: yes, 2012
The novel wheat straw) produced on CIMV pilot plant (France) was sequential extracted with organic solvents of different polarity (dichloromethane, methanol and dichloromethane/methanol mixture.
Arshanitsa, Alexandr   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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