Results 71 to 80 of about 165,624 (327)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Effects of organic selenium on the milk productivity in Saanen goats [PDF]

BIO Web of Conferences
The aim of the research is to evaluate the efficacy of the organic selenium in the diets of lactating goats in terms of lactation performance increase. The objective of the research is to study the effect of feeding the organic form of selenium on goat ...
Syrovatskiy Maxim, Novitskiy Artem, Bagdasarian Elina   +2 more
doaj   +1 more source

Organic acids supplementation in poultry nutrition: a review

Open Veterinary Journal
The poultry industry is continually exploring new feed additives to enhance poultry productivity and health. Since the European Union’s (EU) 2006 ban on antibiotics as growth promoters, alternative methods have become essential to support health and growth in livestock production.
Gerzilov, Vasko, Hristakieva, Pavlina
openaire   +2 more sources

Supplementing Tuberculosis Surveillance with Automated Data from Health Maintenance Organizations [PDF]

Emerging Infectious Diseases, 1999
Data collected by health maintenance organizations (HMOs), which provide care for an increasing number of persons with tuberculosis (TB), may be used to complement traditional TB surveillance. We evaluated the ability of HMO-based surveillance to contribute to overall TB reporting through the use of routinely collected automated data for approximately ...
Deborah S. Yokoe, Girish S. Subramanyan, Edward Nardell, Sharon Sharnprapai, Eugene McCray, Richard Platt   +5 more
openaire   +3 more sources

Forage herbs improve mineral composition of grassland herbage [PDF]

, 2011
Provision of an adequate mineral supply in the diets of ruminants fed mainly on grassland herbage can present a challenge if mineral concentrations are suboptimal for animal nutrition.
Eriksen, Jørgen, Høgh-Jensen, Henning, Pirhofer-Walzl , K., Rasmussen , Jim, Rasmussen, Jesper, Sanderson, M.A., Søegaard, Karen   +6 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Growth, feed conversion ratio and nutrient Metabolizability of broiler chicks fed on inorganic, organic and nano zinc supplemented diets [PDF]

, 2021
Shubhnish, V. S. Panwar, BS Tewatia, Jyotsana Jyotsana   +3 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Assessment of iron supplementation in organic piglets

, 2021
Cette étude vise à décrire les paramètres hématologiques des porcelets aux alentours du sevrage dans des élevages biologiques de plein air ou en bâtiment. Des échantillons de sang étaient prélevés sur 28,9 ± 2,6 porcelets/élevage à 42,0 ± 3,2 jours d'âge et 11,9 ± 3,0 kg de poids vif (moyenne ± ET) dans 21 élevages de l'ouest de la France. Parmi les 11
Prunier, Armelle, Pauwels, Maud, Jaillardon, Laëtitia, Leblanc-Maridor, Mily, Hervé, Gwendoline, Muller, Vincent, Belloc, Catherine, Merlot, Elodie   +7 more
openaire   +1 more source