Results 21 to 30 of about 1,401,210 (353)

Development of Self-Assembling bis-1,4-Dihydropyridines: Detailed Studies of Bromination of Four Methyl Groups and Bromine Nucleophilic Substitution

open access: yesMolecules, 2023
One of the most important steps in the synthesis of 1,4-dihydropyridine (1,4-DHP) amphiphiles is the bromination of methyl groups in positions 2 and 6 of the entire ring.
Martins Kaukulis   +4 more
doaj   +1 more source

Inorganic–organic nanocomposites of CdSe nanocrystals surface-modified with oligo- and poly(fluorene) moieties [PDF]

open access: yes, 2011
We report a facile grafting-from strategy towards the synthesis of inorganic–organic composites of semiconductor nanocrystals and wide-bandgap polymers.
Adamczyk, Sylwia   +12 more
core   +1 more source

Olaparib Conjugates with Selenopheno[3,2-c]quinolinone Inhibit PARP1 and Reverse ABCB1-Related Multidrug Resistance

open access: yesPharmaceutics, 2022
The restoration of the efficacy of antitumor medicines is a cornerstone in the combat with multidrug resistant (MDR) cancers. The overexpression of the ABCB1 transporter is a major obstacle to conventional doxorubicin therapy.
Marina Makrecka-Kuka   +3 more
doaj   +1 more source

Synthesis of porous silicates [PDF]

open access: yes, 1995
The issues of importance and future concern in the synthesis of porous silicates and porous materials that contain a large fraction of silica, e.g. zeolites and other crystalline molecular sieves, are reviewed. The thermodynamics of zeolite synthesis are
Davis­, M. E., Helmkamp, M. M.
core   +1 more source

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

open access: yesMolecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante   +9 more
doaj   +1 more source

Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor®

open access: yesMolecules, 2020
New fluorinated 3,6-dihydropyridines were obtained by the electrophilic fluorination of 1,2-dihydropyridines with Selectfluor®. These 3-fluoro-3,6-dihydropyridines were easily converted to corresponding pyridines by the elimination of hydrogen fluoride ...
Nadiia V. Pikun   +8 more
doaj   +1 more source

The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A

open access: yesPharmaceuticals, 2021
The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimidines and S-
Egils Bisenieks   +11 more
doaj   +1 more source

Influence of coffee brewing methods on the chromatographic and spectroscopic profiles, antioxidant and sensory properties

open access: yesScientific Reports, 2021
Cold brewing coffee has gained increasing popularity as a novel brewing method. A completely different flavour profile during cold brewing extraction (smooth and mild) is a result of the low-energy process, prolonged water-grind contact times and long ...
Natalia Stanek   +9 more
doaj   +1 more source

Organic crystalline polymers: structural properties and way to synthesis under high pressure

open access: yes, 2018
We consider different structures, which can be obtained by polymerization of aromatic organic molecules under high pressures. These 2D and 3D covalently bonded organic polymers and their functionalization can pave the way to production of energy storage ...
Brazhkin, V. V.   +4 more
core   +1 more source

Synthesis and Evaluation of Self-Assembling Properties of 3-(3,5-Difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium Iodides

open access: yesMolbank, 2022
A synthesis of 3-(3,5-difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium iodides with ethyl or nonyl ester groups at positions 3 and 5 was performed. Treatment of the corresponding 2’,6’-dimethyl-1’,4’-dihydro-[3,4’-bipyridine]
Nadiia Pikun   +6 more
doaj   +1 more source

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