Results 31 to 40 of about 4,566,280 (295)
The digitization of organic synthesis [PDF]
Nature, 2019 Organic chemistry has largely been conducted in an ad hoc manner by academic laboratories that are funded by grants directed towards the investigation of specific goals or hypotheses. Although modern synthetic methods can provide access to molecules of considerable complexity, predicting the outcome of a single chemical reaction remains a major ...
openaire +2 more sources
Improved method for the obtaining DTTA-appended 2,2’-bipyridine ligands for lanthanide cations
Chimica Techno Acta, 2022 The composition of the reaction mixture after DTTA tert-butyl ester alkylation with 6'-halomethyl-5-phenyl-2,2'-bipyridines was studied. In addition to the target product, DTTA-appended 2,2’-bipyridine, the corresponding 6'-hydroxymethyl-substituted 2,2’-
Dmitry S. Kopchuk +9 more
doaj +1 more source
Optimization in organic synthesis [PDF]
Medicinal Research Reviews, 1999 Organic Synthesis, quo vadis?3 has been a phrase, perhaps in a more modern language, on the lips of the practitioners of this demanding science-art, undoubtedly from the earliest times4 but more vigorously in the last two decades.5 Comparison of achievements of yesterday6 and today7 suggests progress in our abilities to construct molecules of ...
openaire +2 more sources
Conjugated Ynones in Organic Synthesis [PDF]
Chemical Reviews, 2019 This review article will consider the preparation and application of ynones in synthetic organic chemistry. Concerning the preparation of these bifunctional compounds, several methodologies starting from propargyl alcohols, acyl derivatives, both by using alkynylmetal reagents or by transition metal (mainly palladium and copper) catalyzed alkynylations,
Carmen Nájera +2 more
openaire +4 more sources
Czech Journal of Food Sciences, 2001 Antioxidants with 1,4-dihydropyridine structure were investigated as a less harmful alternative to synthetic phenolic antioxidants in liposomes under conditions simulating food storage.
G. Tirzitis, D. Tirzite, Z. Hyvonen
doaj +1 more source
Molecules, 2023 One of the most important steps in the synthesis of 1,4-dihydropyridine (1,4-DHP) amphiphiles is the bromination of methyl groups in positions 2 and 6 of the entire ring.
Martins Kaukulis +4 more
doaj +1 more source
Origins of Organic Chemistry and Organic Synthesis
European Journal of Organic Chemistry, 2022 AbstractThe words organic and synthesis originate with Aristotle (meaning ‘instrumental’ and ‘put together’, respectively) but had different meanings over time. The iatrochemists prepared numerous pharmaceutical remedies in the 1600s but had no concept of organic chemistry.
openaire +3 more sources
Molecules, 2020 New fluorinated 3,6-dihydropyridines were obtained by the electrophilic fluorination of 1,2-dihydropyridines with Selectfluor®. These 3-fluoro-3,6-dihydropyridines were easily converted to corresponding pyridines by the elimination of hydrogen fluoride ...
Nadiia V. Pikun +8 more
doaj +1 more source
Pharmaceutics, 2022 The restoration of the efficacy of antitumor medicines is a cornerstone in the combat with multidrug resistant (MDR) cancers. The overexpression of the ABCB1 transporter is a major obstacle to conventional doxorubicin therapy.
Marina Makrecka-Kuka +3 more
doaj +1 more source
Maintaining ecological soil functions - techniques in organic farming systems [PDF]
, 2000 The ecological soil functions (e.g. habitat and living space, production and utilization, ecological regulation) have to be taken into account and maintained by farming systems.
Beste, Andrea
core +1 more source