Results 41 to 50 of about 4,566,280 (295)

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Molecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev   +9 more
doaj   +1 more source

The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A

Pharmaceuticals, 2021
The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimidines and S-
Egils Bisenieks, Brigita Vigante, Ramona Petrovska, Baiba Turovska, Ruslan Muhamadejev, Vitalijs Soloduns, Astrida Velena, Karlis Pajuste, Luciano Saso, Janis Klovins, Gunars Duburs, Ilona Mandrika   +11 more
doaj   +1 more source

Vinylepoxides in Organic Synthesis

, 2006
Vinylepoxides have become important intermediates in organic synthesis. The main reason for this is the development of selective methods for their subsequent transformations.
Berit Olofsson, Peter Somfai, Somfai, Peter,, Olofsson, Berit,, Olofsson, B.   +4 more
core   +1 more source

Influence of coffee brewing methods on the chromatographic and spectroscopic profiles, antioxidant and sensory properties

Scientific Reports, 2021
Cold brewing coffee has gained increasing popularity as a novel brewing method. A completely different flavour profile during cold brewing extraction (smooth and mild) is a result of the low-energy process, prolonged water-grind contact times and long ...
Natalia Stanek, Magdalena Zarębska, Łukasz Biłos, Krzysztof Barabosz, Ewa Nowakowska-Bogdan, Izabela Semeniuk, Justyna Błaszkiewicz, Renata Kulesza, Rafał Matejuk, Krzysztof Szkutnik   +9 more
doaj   +1 more source

Approaches to the Total Synthesis of Conduramines: A Review

SynOpen, 2022
This review reports on the total synthesis of conduramines, which are formally derived from conduritols, mainly containing a trihydroxy aminocyclohexene core.
Hanumantharayappa Bharathkumar, Jattuboyina Siva Krishna, Banothu Surender, Venkateswara Rao Batchu   +3 more
doaj   +1 more source

The contribution of research to the development of organic farming in Europe [PDF]

, 2002
On national as well as on EU level, research funds should be directed substantially towards organic farming in order to improve the economic and ecological performance of organic farming.
Niggli, Urs
core   +1 more source

Synthesis and Evaluation of Self-Assembling Properties of 3-(3,5-Difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium Iodides

Molbank, 2022
A synthesis of 3-(3,5-difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium iodides with ethyl or nonyl ester groups at positions 3 and 5 was performed. Treatment of the corresponding 2’,6’-dimethyl-1’,4’-dihydro-[3,4’-bipyridine]
Nadiia Pikun, Davis Lacis, Arkadij Sobolev, Martins Rucins, Mara Plotniece, Karlis Pajuste, Aiva Plotniece   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Silacyclohex-4-enes: novel silene-cycloadducts for organic synthesis [PDF]

, 2008
Silenes, compounds containing a Si=c double bond, are highly reactive and are normally observed as transient intermediates which readily dimerise. Evidence for their existence was first reported in 1967 by Gusel'nikov and Flowers.(^1) However, since then
Sellars, Jonathan D., Sellars, Jonathan D   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source