Results 51 to 60 of about 4,566,280 (295)

The roots of organic agriculture [PDF]

open access: yes, 2012
It was concern about the replacement of traditional organic fertilizers by the then new chemical fertilizers that precipitated the early stirrings of disquiet about the prevailing direction of agriculture and which has grown into today’s organic ...
Paull, John
core   +1 more source

The synthesis of 5-substituted hydantoins [PDF]

open access: yes, 2008
The Bucherer-Bergs reaction is a classical multi-component reaction that yields hydantoins, which can be hydrolysed to afford α-amino acids. Hydantoins have many uses in modern organic synthesis, and this moiety has been included in a number of ...
Murray, Ross George
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Applications of DABSO for the delivery of sulfur dioxide in organic synthesis [PDF]

open access: yes, 2015
This thesis documents the development of novel synthetic methodologies for the incorporation of sulfur dioxide into organic molecules employing the amine-sulfur dioxide complex DABSO (vide infra).
Deeming, Alex
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Copper-catalyzed enantioselective hydroamination of alkenes

open access: yes, 2019
[Graphic representation of three chemical reactions, labelled A., B., and C.]National Institutes of Health (award no ...
Buchwald, Stephen Leffler, Liu, Richard
core   +1 more source

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions

open access: yesBeilstein Journal of Organic Chemistry, 2015
Stable heterocyclic hydroperoxide can be easily prepared as a product of fast oxidation of a 1,2,3,4-tetrahydropyridine by 3O2 if the solution is exposed to sunlight.
Baiba Turovska   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The World of Organic Agriculture: Statistics and Future Prospects 2003 [PDF]

open access: yes, 2003
This study documents concisely recent developments in global organic agriculture. Apart from figures on the area under organic management and on organic farms this publication also contains general information on the state of organic agriculture in the ...

core   +1 more source

S9 protease WprP2 catalyzes uniform cleavage on the precursor peptide in RiPP biosynthesis

open access: yesCommunications Chemistry
Serine proteases in ribosomally synthesized and post-translationally modified peptides (RiPPs) catalyze the cleavage on the precursor peptides in the biosynthesis of RiPP natural products. Here, we identified an uncharacterized serine protease WprP2 from
Jabal Rahmat Haedar   +4 more
doaj   +1 more source

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