Results 121 to 130 of about 2,401,395 (295)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Organizing as a mode of existence
Revue d'anthropologie des connaissancesThis article explores Bruno Latour's innovative perspectives on the study of organisations. It goes back to his speech at EGOS in 1993. In it he asked what the sociology of science could contribute to the study of organisation.
Barbara Czarniawska
doaj +1 more source
The Necessary Architecture of Self-Regulating Teams [PDF]
, 1997 In this paper we present the meaning of self-regulation in Self- Regulating Teams (SRTs) and show the importance of self- regulating teams in a learning organisation.
Johnson, Leslie, Stergiou, Maria
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Lessons for integration from 70 primary care projects
International Journal of Integrated Care, 2014 Marc A Bruijnzeels +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Self-Organising Agent Organisations
, 2009 Self-organising multi-agent systems provide a suitable paradigm for developing autonomic computing systems that manage themselves. Towards this goal, we demonstrate a robust, decentralised approach for structural adaptation in explicitly modelled problem solving agent organisations.
Kota, Ramachandra +2 more
openaire +2 more sources
Reconceptualising the third sector: toward a heterodox perspective [PDF]
The paper explores the way the work of classic institutionalist authors can inform modern nonprofit economics. From the perspective of Thorstein Veblen, nonprofit organisation is explained as an institutional consequence of the pecuniary-industrial ...
Vladislav Valentinov
core
Understanding customer satisfaction based on the way they evaluate service delivery [PDF]
, 2018 With the development of society, the service industry has become the pillar of the world economy. People's demand for service products is getting higher and higher because people are becoming increasing lazy.
Abarashi, Jamal, Li, Jiqiu
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